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  2. GPCR/G Protein
  3. GnRH Receptor
  4. Luteinizing Hormone Releasing Hormone (LH-RH), salmon

Luteinizing Hormone Releasing Hormone (LH-RH), salmon  (Synonyms: Salmon GnRH; Salmon gonadotropin-releasing hormone; sGnRH)

目錄號(hào): HY-P0243 純度: 99.69%
COA 產(chǎn)品使用指南 技術(shù)支持

Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) 是在下丘腦中合成的垂體前體十肽，在控制生殖功能中起關(guān)鍵作用。

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Custom Peptide Synthesis

Luteinizing Hormone Releasing Hormone (LH-RH), salmon Chemical Structure

Luteinizing Hormone Releasing Hormone (LH-RH), salmon Chemical Structure

CAS No. : 86073-88-3

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     可免費(fèi)申領(lǐng)三個(gè)不同產(chǎn)品的試用裝。

3.  試用裝只面向終端客戶。

規(guī)格 價(jià)格 是否有貨 數(shù)量
1 mg ￥880
In-stock
5 mg ￥1950
In-stock
10 mg ￥3500
In-stock
50 mg   詢價(jià)  
100 mg   詢價(jià)  

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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.

體外研究
(In Vitro)

促黃體激素釋放激素 (LHRH) 是控制生殖功能的關(guān)鍵激素。LHRH 通過(guò)激活 Gi-cAMP 細(xì)胞內(nèi)信號(hào)通路作為抗有絲分裂因子。LHRH 可能作為黑色素瘤細(xì)胞增殖和轉(zhuǎn)移行為的抑制因子[1]。下丘腦十肽促黃體激素釋放激素 (LHRH) 通過(guò)刺激垂體促黃體激素 (LH) 和促卵泡激素 (FSH) 的釋放，在控制生殖方面發(fā)揮核心作用，進(jìn)而促進(jìn)性腺功能并調(diào)節(jié)性類固醇分泌。LHRH 的作用是由高親和力 G 蛋白偶聯(lián) LHRH 受體 (LHRH-R) 對(duì)垂體促性腺激素介導(dǎo)的。對(duì) LHRH 的反應(yīng)在不同條件下會(huì)有所不同，并且主要取決于給藥方案和遞送至促性腺激素細(xì)胞的劑量[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1212.31

Formula

C60H73N15O13
CAS 號(hào)
性狀

固體

顏色

White to off-white

Sequence

{Glp}-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-NH2
Sequence Shortening

{Glp}-HWSYGWLPG-NH2
中文名稱

黃體激素釋放激素 (LH-RH),蛙魚(yú)
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
細(xì)胞實(shí)驗(yàn)： 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

Luteinizing Hormone Releasing Hormone (LH-RH), salmon 相關(guān)分類

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Luteinizing Hormone Releasing Hormone (LH-RH), salmon
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