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  2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. Spiraeoside

Spiraeoside  (Synonyms: Quercetin 4′-O-glucoside)

目錄號: HY-N8253 純度: 99.46%
COA 產(chǎn)品使用指南 技術支持

Spiraeoside 是具有口服活性的天然產(chǎn)物，具有抗氧化活性，抑制活性氧和丙二醛的生成。Spiraeoside 具有抗過敏、抗炎、抗腫瘤活性。

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Spiraeoside Chemical Structure

Spiraeoside Chemical Structure

CAS No. : 20229-56-5

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥1900
In-stock
5 mg ￥4800
In-stock
10 mg 現(xiàn)貨 詢價
50 mg   詢價  
100 mg   詢價  

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Customer Review

Other Forms of Spiraeoside:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Spiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities[1].

細胞效力
(Cellular Effect)
Cell Line Type Value Description References
B16-4A5 IC50
> 100 μM
Compound: 8
Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells after 72 hrs by microplate reader analysis
Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells after 72 hrs by microplate reader analysis
[PMID: 25987378]
體外研究
(In Vitro)

Spiraeoside 提高 HG 刺激-引起 AC16 細胞中 p-Akt、核 Nrf2 和 HO-1 表達水平的降低 (Spiraeoside 的作用被 LY294002 逆轉)[1]。
Spiraeoside 保護 AC16 細胞免受 HG 誘導的氧化應激、細胞損傷和細胞凋亡[1]。
Spiraeoside 在暴露于 HG 時激活 AC16 細胞中的 PI3K/Akt/Nrf2 通路[1]。
螺內酯通過 PI3K/Akt/Nrf2 通路保護 AC16 細胞免受 HG 誘導的細胞凋亡[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: AC16 cells.
Concentration: 1, 5, 10, or 20 μM.
Incubation Time: 0, 24, or 48 hours.
Result: Inhibited AC16 cells viability (20 μM).
體內研究
(In Vivo)

Spiraeoside (50 mg/kg，po) 具有預防潰瘍的能力[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar rats (6-8 weeks old)[2].
Dosage: 50 mg/kg.
Administration: Oral gavage an hour before inducing the lesions.
Result: Decreased severity of the formed lesions.
分子量

464.38

Formula

C21H20O12
CAS 號
性狀

固體

顏色

Light yellow to yellow

中文名稱

螺旋藻苷
結構分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

純度 & 產(chǎn)品資料

純度: 99.46%

參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Spiraeoside
目錄號：
HY-N8253
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