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  2. 天然產(chǎn)物
  3. 植物 疾病研究領(lǐng)域 萜類
  4. 菊科 其他 傘形科 三萜
  5. 傘序托鞭菊 Lychnophora antillana
  6. 6''-O-Acetylsaikosaponin A

6''-O-Acetylsaikosaponin A，從柴胡根中分離得到的乙酰柴胡皂苷，具有一定的破骨細胞抑制活性。

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6''-O-Acetylsaikosaponin A Chemical Structure

6''-O-Acetylsaikosaponin A Chemical Structure

CAS No. : 64340-46-1

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥2200
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  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

6''-O-Acetylsaikosaponin A, an acetyl saikosaponin isolated from the roots of Bupleurum chinense, shows some osteoclast-inhibiting activities[1].

細胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
35.32 μM
Compound: 13
Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
Bcap37 IC50
34.13 μM
Compound: 13
Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
Hep 3B2 IC50
16.93 μM
Compound: 13
Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
HepG2 IC50
20.81 μM
Compound: 13
Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
MCF7 IC50
36.22 μM
Compound: 13
Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
體外研究
(In Vitro)

The major bioactive compounds isolated from R. bupleuri are saikosaponins, which have been proved to possess significant biological activities, including anti-hepatitis, anti-inflammatory, anti-tumor and immunoregulatory effects[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

823.02

Formula

C44H70O14
CAS 號
性狀

固體

顏色

White to off-white

結(jié)構(gòu)分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性數(shù)據(jù)
細胞實驗： 

DMSO 中的溶解度 : 100 mg/mL (121.50 mM; 超聲助溶; 吸濕的 DMSO 對產(chǎn)品的溶解度有顯著影響，請使用新開封的 DMSO)

配制儲備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 1.2150 mL 6.0752 mL 12.1504 mL
5 mM 0.2430 mL 1.2150 mL 2.4301 mL
查看完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲存時，請在6個月內(nèi)使用，-20°C儲存時，請在1個月內(nèi)使用。

  • 摩爾計算器

  • 稀釋計算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動物溶解方案計算器
請輸入動物實驗的基本信息：

給藥劑量

mg/kg

動物的平均體重

g

每只動物的給藥體積

μL

動物數(shù)量

只
由于實驗過程有損耗，建議您多配一只動物的量
計算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料
參考文獻

完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲存時，請在6個月內(nèi)使用，-20°C儲存時，請在1個月內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2150 mL 6.0752 mL 12.1504 mL 30.3759 mL
5 mM 0.2430 mL 1.2150 mL 2.4301 mL 6.0752 mL
10 mM 0.1215 mL 0.6075 mL 1.2150 mL 3.0376 mL
15 mM 0.0810 mL 0.4050 mL 0.8100 mL 2.0251 mL
20 mM 0.0608 mL 0.3038 mL 0.6075 mL 1.5188 mL
25 mM 0.0486 mL 0.2430 mL 0.4860 mL 1.2150 mL
30 mM 0.0405 mL 0.2025 mL 0.4050 mL 1.0125 mL
40 mM 0.0304 mL 0.1519 mL 0.3038 mL 0.7594 mL
50 mM 0.0243 mL 0.1215 mL 0.2430 mL 0.6075 mL
60 mM 0.0203 mL 0.1013 mL 0.2025 mL 0.5063 mL
80 mM 0.0152 mL 0.0759 mL 0.1519 mL 0.3797 mL
100 mM 0.0122 mL 0.0608 mL 0.1215 mL 0.3038 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
6''-O-Acetylsaikosaponin A
目錄號：
HY-N7613
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