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  2. 天然產(chǎn)物
  3. 疾病研究領(lǐng)域 植物 萜類
  4. 其他科 癌癥 倍半萜
  5. Helenium microcephalum
  6. Microhelenin C

Microhelenin C  (Synonyms: 小堆心菊素C)

目錄號: HY-N7595 純度: 99.55%
COA 產(chǎn)品使用指南 技術(shù)支持

Microhelenin C 是一種倍半萜內(nèi)酯，能從 Helenium microcephalum 中提取得到，具有抗腫瘤活性。

MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報(bào)，我們不為任何個人用途提供產(chǎn)品和服務(wù)

Microhelenin C Chemical Structure

Microhelenin C Chemical Structure

CAS No. : 63569-07-3

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規(guī)格 價(jià)格 是否有貨 數(shù)量
1 mg ￥1060
In-stock
5 mg ￥2900
In-stock
10 mg   詢價(jià)  
50 mg   詢價(jià)  

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  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Microhelenin C is a sesquiterpene lactone that can be isolated from Helenium microcephalum, with antitumor activity[1].

細(xì)胞效力
(Cellular Effect)
Cell Line Type Value Description References
HCT-116 IC50
> 10 μM
Compound: 19
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 33533247]
HeLa IC50
> 10 μM
Compound: 19
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 33533247]
HepG2 IC50
> 10 μM
Compound: 19
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 33533247]
RAW264.7 IC50
> 10 μM
Compound: 19
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess reagent based assay
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess reagent based assay
[PMID: 33533247]
分子量

346.42

Formula

C20H26O5
CAS 號
性狀

固體

顏色

White to light yellow

中文名稱

小堆心菊素C
結(jié)構(gòu)分類
初始來源
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性數(shù)據(jù)
細(xì)胞實(shí)驗(yàn)： 

DMSO 中的溶解度 : 100 mg/mL (288.67 mM; 超聲助溶; 吸濕的 DMSO 對產(chǎn)品的溶解度有顯著影響，請使用新開封的 DMSO)

配制儲備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 2.8867 mL 14.4333 mL 28.8667 mL
5 mM 0.5773 mL 2.8867 mL 5.7733 mL
查看完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲存時，請?jiān)?個月內(nèi)使用，-20°C儲存時，請?jiān)?個月內(nèi)使用。

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  • 稀釋計(jì)算器

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