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  2. Vitamin D Related/Nuclear Receptor Apoptosis
  3. Androgen Receptor Apoptosis
  4. Isosilybin B

Isosilybin B  (Synonyms: 異水飛薊賓B)

目錄號: HY-N7045 純度: ≥98.0%
COA 產(chǎn)品使用指南

Isosilybin B，一種從水飛薊中分離的黃酮木脂素，具有抗前列腺癌 (PCA) 活性，抑制癌細胞增殖，誘導 G1 期阻滯和凋亡。Isosilybin B 引起雄激素受體降解。

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Isosilybin B Chemical Structure

Isosilybin B Chemical Structure

CAS No. : 142796-22-3

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥1400
In-stock
5 mg ￥3500
In-stock
10 mg   詢價  
50 mg   詢價  

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Other Forms of Isosilybin B:

MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Isosilybin B, a flavonolignan isolated from Silybum marianum, has anti-prostate cancer (PCA) activity via inhibiting proliferation and inducing G1 phase arrest and apoptosis. Isosilybin B causes androgen receptor (AR) degradation[1][2].

細胞效力
(Cellular Effect)
Cell Line Type Value Description References
B16-4A5 IC50
6.1 μM
Compound: 8
Inhibition of theophylline-stimulated melanogenesis in mouse B16-4A5 cells after 72 hrs
Inhibition of theophylline-stimulated melanogenesis in mouse B16-4A5 cells after 72 hrs
[PMID: 20189399]
Huh-7 IC50
27 μM
Compound: 7
Cytotoxicity against human Huh7.5.1 cells after 72 hrs
Cytotoxicity against human Huh7.5.1 cells after 72 hrs
[PMID: 23673225]
分子量

482.44

Formula

C25H22O10
CAS 號
性狀

固體

顏色

White to off-white

中文名稱

異水飛薊賓B
結(jié)構(gòu)分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料
參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Isosilybin B
目錄號：
HY-N7045
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