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  4. 3-Acetyl-beta-boswellic acid

3-Acetyl-beta-boswellic acid 是從乳香鋸緣膠樹脂中分離得到的乳香酸。

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3-Acetyl-beta-boswellic acid Chemical Structure

3-Acetyl-beta-boswellic acid Chemical Structure

CAS No. : 5968-70-7

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Other Forms of 3-Acetyl-beta-boswellic acid:

MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻(xiàn)

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

3-Acetyl-beta-boswellic acid is a boswellic acid isolated from Boswellia serrata gum resin[1].

細(xì)胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
3 μM
Compound: 3
Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis
Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis
[PMID: 24844534]
HeLa IC50
22 μM
Compound: 3, ABA
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
[PMID: 21334793]
HL-60 IC50
10 μM
Compound: 3, ABA
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
[PMID: 21334793]
HUVEC IC50
> 100 μM
Compound: 2, ABA
Antiproliferation activity against HUVEC cells after 48 hrs by CCK-8 assay
Antiproliferation activity against HUVEC cells after 48 hrs by CCK-8 assay
[PMID: 25819335]
Sf21 IC50
> 40 μM
Compound: 28
Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis
Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis
[PMID: 31774676]
分子量

498.74

Formula

C32H50O4

CAS 號(hào)
性狀

固體

顏色

White to off-white

結(jié)構(gòu)分類
初始來源
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性數(shù)據(jù)
細(xì)胞實(shí)驗(yàn): 

DMSO 中的溶解度 : 100 mg/mL (200.51 mM; 超聲助溶 (<60°C); 吸濕的 DMSO 對(duì)產(chǎn)品的溶解度有顯著影響,請(qǐng)使用新開封的 DMSO)

配制儲(chǔ)備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 2.0051 mL 10.0253 mL 20.0505 mL
5 mM 0.4010 mL 2.0051 mL 4.0101 mL
查看完整儲(chǔ)備液配制表

* 請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液;一旦配成溶液,請(qǐng)分裝保存,避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C儲(chǔ)存時(shí),請(qǐng)?jiān)?個(gè)月內(nèi)使用,-20°C儲(chǔ)存時(shí),請(qǐng)?jiān)?個(gè)月內(nèi)使用。

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動(dòng)物溶解方案計(jì)算器
請(qǐng)輸入動(dòng)物實(shí)驗(yàn)的基本信息:

給藥劑量

mg/kg

動(dòng)物的平均體重

g

每只動(dòng)物的給藥體積

μL

動(dòng)物數(shù)量

由于實(shí)驗(yàn)過程有損耗,建議您多配一只動(dòng)物的量
計(jì)算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料

純度: 98.10%

參考文獻(xiàn)

完整儲(chǔ)備液配制表

* 請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液;一旦配成溶液,請(qǐng)分裝保存,避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C儲(chǔ)存時(shí),請(qǐng)?jiān)?個(gè)月內(nèi)使用,-20°C儲(chǔ)存時(shí),請(qǐng)?jiān)?個(gè)月內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0051 mL 10.0253 mL 20.0505 mL 50.1263 mL
5 mM 0.4010 mL 2.0051 mL 4.0101 mL 10.0253 mL
10 mM 0.2005 mL 1.0025 mL 2.0051 mL 5.0126 mL
15 mM 0.1337 mL 0.6684 mL 1.3367 mL 3.3418 mL
20 mM 0.1003 mL 0.5013 mL 1.0025 mL 2.5063 mL
25 mM 0.0802 mL 0.4010 mL 0.8020 mL 2.0051 mL
30 mM 0.0668 mL 0.3342 mL 0.6684 mL 1.6709 mL
40 mM 0.0501 mL 0.2506 mL 0.5013 mL 1.2532 mL
50 mM 0.0401 mL 0.2005 mL 0.4010 mL 1.0025 mL
60 mM 0.0334 mL 0.1671 mL 0.3342 mL 0.8354 mL
80 mM 0.0251 mL 0.1253 mL 0.2506 mL 0.6266 mL
100 mM 0.0201 mL 0.1003 mL 0.2005 mL 0.5013 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱:
3-Acetyl-beta-boswellic acid
目錄號(hào):
HY-N2075
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