成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

  2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. COX Lipoxygenase
  4. Pectolinarigenin

Pectolinarigenin  (Synonyms: 柳穿魚(yú)黃素)

目錄號(hào): HY-N0493 純度: 99.59%
COA 產(chǎn)品使用指南 技術(shù)支持

Pectolinarigenin 是 COX-2/5-LOX 的雙重抑制劑。具有抗炎活性。Pectolinarigenin 對(duì)黑素生成具有有效的抑制作用。

MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報(bào)，我們不為任何個(gè)人用途提供產(chǎn)品和服務(wù)

Pectolinarigenin Chemical Structure

Pectolinarigenin Chemical Structure

CAS No. : 520-12-7

1.  客戶(hù)無(wú)需承擔(dān)相應(yīng)的運(yùn)輸費(fèi)用。

2.  同一機(jī)構(gòu)（單位）同一產(chǎn)品試用裝僅限申領(lǐng)一次，同一機(jī)構(gòu)（單位）一年內(nèi)

     可免費(fèi)申領(lǐng)三個(gè)不同產(chǎn)品的試用裝。

3.  試用裝只面向終端客戶(hù)。

規(guī)格 價(jià)格 是否有貨 數(shù)量
1 mg ￥476
In-stock
5 mg ￥1190
In-stock
10 mg ￥2020
In-stock
20 mg ￥3430
In-stock
50 mg   詢(xún)價(jià)  
100 mg   詢(xún)價(jià)  

* Please select Quantity before adding items.

Customer Review

Other Forms of Pectolinarigenin:

MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻(xiàn)

查看 COX 亞型特異性產(chǎn)品:

查看 Lipoxygenase 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Pectolinarigenin is a dual inhibitor of COX-2/5-LOX. Anti-inflammatory activity[1]. Pectolinarigenin has potent inhibitory activities on melanogenesis[2].

IC50 & Target[1]

COX-2

 

5-LOX

 

細(xì)胞效力
(Cellular Effect)
Cell Line Type Value Description References
A-375 IC50
8.2 μM
Compound: 2
Antiproliferative activity against human A375 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A375 cells after 48 hrs by sulforhodamine B assay
[PMID: 18818071]
A549 IC50
5.6 μM
Compound: 2
Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
[PMID: 18818071]
ACHN IC50
15.2 μM
Compound: 2
Antiproliferative activity against human ACHN cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human ACHN cells after 48 hrs by sulforhodamine B assay
[PMID: 18818071]
C32 IC50
7 μM
Compound: 2
Antiproliferative activity against human C32 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human C32 cells after 48 hrs by sulforhodamine B assay
[PMID: 18818071]
Caco-2 IC50
5.3 μM
Compound: 2
Antiproliferative activity against human Caco-2 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human Caco-2 cells after 48 hrs by sulforhodamine B assay
[PMID: 18818071]
COR-L23 IC50
4.1 μM
Compound: 2
Antiproliferative activity against human COR-L23 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human COR-L23 cells after 48 hrs by sulforhodamine B assay
[PMID: 18818071]
HepG2 IC50
18.1 μM
Compound: 2
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
[PMID: 30579802]
Jurkat IC50
> 20 μM
Compound: 2
Immunosuppressive activity in human Jurkat cells assessed as reduction in PHA + PMA-induced IL-2 production after 48 hrs by ELISA
Immunosuppressive activity in human Jurkat cells assessed as reduction in PHA + PMA-induced IL-2 production after 48 hrs by ELISA
[PMID: 30579802]
L6 IC50
20.2 μM
Compound: 24
Cytotoxicity against rat L6 cells after 72 hrs by alamar blue staining based fluorescence assay
Cytotoxicity against rat L6 cells after 72 hrs by alamar blue staining based fluorescence assay
[PMID: 29244495]
MOLM-13 IC50
5.9 μM
Compound: 32
Cytotoxicity against human MOLM-13 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human MOLM-13 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 33393294]
MV4-11 IC50
7.9 μM
Compound: 32
Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
[PMID: 33393294]
NCI-H1975 IC50
76.6 μM
Compound: 2
Cytotoxicity against human NCI-H1975 cells after 72 hrs by MTT assay
Cytotoxicity against human NCI-H1975 cells after 72 hrs by MTT assay
[PMID: 30579802]
PC-9 IC50
> 80 μM
Compound: 2
Cytotoxicity against human PC9 cells after 72 hrs by MTT assay
Cytotoxicity against human PC9 cells after 72 hrs by MTT assay
[PMID: 30579802]
RAW264.7 IC50
> 20 μM
Compound: 2
Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced TNF-alpha production after 48 hrs by ELISA
Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced TNF-alpha production after 48 hrs by ELISA
[PMID: 30579802]
RAW264.7 IC50
> 20 μM
Compound: 2
Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced IL-6 production after 48 hrs by ELISA
Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced IL-6 production after 48 hrs by ELISA
[PMID: 30579802]
Sf9 IC50
0.6 μM
Compound: 1
Inhibition of N-terminal GST-His-tagged c-KIT (544 to 976 amino acids) D816V mutant (unknown origin) expressed in Sf9 insect cells using poly[Glu:Tyr] (4:1) as substrate preincubated for 20 mins followed by [33P-gamma]ATP addition and subsequent inhibitio
Inhibition of N-terminal GST-His-tagged c-KIT (544 to 976 amino acids) D816V mutant (unknown origin) expressed in Sf9 insect cells using poly[Glu:Tyr] (4:1) as substrate preincubated for 20 mins followed by [33P-gamma]ATP addition and subsequent inhibitio
[PMID: 26807861]
分子量

314.29

Formula

C17H14O6
CAS 號(hào)
性狀

固體

顏色

Light yellow to yellow

中文名稱(chēng)

柳穿魚(yú)黃素
結(jié)構(gòu)分類(lèi)
初始來(lái)源
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性數(shù)據(jù)
細(xì)胞實(shí)驗(yàn)： 

DMSO 中的溶解度 : 33.33 mg/mL (106.05 mM; 超聲助溶; 吸濕的 DMSO 對(duì)產(chǎn)品的溶解度有顯著影響，請(qǐng)使用新開(kāi)封的 DMSO)

配制儲(chǔ)備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 3.1818 mL 15.9089 mL 31.8177 mL
5 mM 0.6364 mL 3.1818 mL 6.3635 mL
查看完整儲(chǔ)備液配制表

* 請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；一旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)月內(nèi)使用，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)月內(nèi)使用。

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動(dòng)物實(shí)驗(yàn)：

請(qǐng)根據(jù)您的 實(shí)驗(yàn)動(dòng)物和給藥方式 選擇適當(dāng)?shù)娜芙夥桨浮?

以下溶解方案都請(qǐng)先按照 In Vitro 方式配制澄清的儲(chǔ)備液，再依次添加助溶劑：
——為保證實(shí)驗(yàn)結(jié)果的可靠性，澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；體內(nèi)實(shí)驗(yàn)的工作液，建議您現(xiàn)用現(xiàn)配，當(dāng)天使用；
以下溶劑前顯示的百分比是指該溶劑在您配制終溶液中的體積占比；如在配制過(guò)程中出現(xiàn)沉淀、析出現(xiàn)象，可以通過(guò)加熱和/或超聲的方式助溶

  • 方案 一

    請(qǐng)依序添加每種溶劑： 2% DMSO    98% (20% SBE-β-CD in Saline)

    Solubility: ≥ 1 mg/mL (3.18 mM); 澄清溶液

以下溶解方案，請(qǐng)直接配制工作液。建議現(xiàn)用現(xiàn)配，在短期內(nèi)盡快用完。 以下溶劑前顯示的百分比是指該溶劑在您配制終溶液中的體積占比； 如在配制過(guò)程中出現(xiàn)沉淀、析出現(xiàn)象，可以通過(guò)加熱和/或超聲的方式助溶。

  • 方案 一

    請(qǐng)依序添加每種溶劑： 50% PEG300    50% Saline

    Solubility: 1 mg/mL (3.18 mM); 懸濁液; 超聲助溶 (<60°C)

動(dòng)物溶解方案計(jì)算器
請(qǐng)輸入動(dòng)物實(shí)驗(yàn)的基本信息：

給藥劑量

mg/kg

動(dòng)物的平均體重

g

每只動(dòng)物的給藥體積

μL

動(dòng)物數(shù)量

只
由于實(shí)驗(yàn)過(guò)程有損耗，建議您多配一只動(dòng)物的量
請(qǐng)輸入您的動(dòng)物體內(nèi)配方組成：
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
如果您的動(dòng)物是免疫缺陷鼠或者體弱鼠，建議 DMSO 中的在最后工作液體系中的占比盡量不超過(guò) 2%。
方案所需 助溶劑 包括：DMSO， ，均可在 MCE 網(wǎng)站選購(gòu)。 ，Tween 80，均可在 MCE 網(wǎng)站選購(gòu)。
計(jì)算結(jié)果
工作液所需濃度 : mg/mL
儲(chǔ)備液配制方法 : mg 藥物溶于 μL  DMSO（母液濃度為 mg/mL）。

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

您所需的儲(chǔ)備液濃度超過(guò)該產(chǎn)品的實(shí)測(cè)溶解度，以下方案僅供參考，如有需要，請(qǐng)與 MCE 中國(guó)技術(shù)支持聯(lián)系。
動(dòng)物實(shí)驗(yàn)體內(nèi)工作液的配制方法 : 取 μL DMSO 儲(chǔ)備液，加入 μL 。 μL ，混合均勻至澄清，再加 μL Tween 80，混合均勻至澄清，再加 μL 生理鹽水。
連續(xù)給藥周期超過(guò)半月以上，請(qǐng)謹(jǐn)慎選擇該方案。
請(qǐng)確保第一步儲(chǔ)備液溶解至澄清狀態(tài)，從左到右依次添加助溶劑。您可采用超聲加熱 （超聲清洗儀，建議頻次 20-40 kHz），渦旋吹打等方式輔助溶解。
純度 & 產(chǎn)品資料
參考文獻(xiàn)

完整儲(chǔ)備液配制表

* 請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；一旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)月內(nèi)使用，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)月內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1818 mL 15.9089 mL 31.8177 mL 79.5444 mL
5 mM 0.6364 mL 3.1818 mL 6.3635 mL 15.9089 mL
10 mM 0.3182 mL 1.5909 mL 3.1818 mL 7.9544 mL
15 mM 0.2121 mL 1.0606 mL 2.1212 mL 5.3030 mL
20 mM 0.1591 mL 0.7954 mL 1.5909 mL 3.9772 mL
25 mM 0.1273 mL 0.6364 mL 1.2727 mL 3.1818 mL
30 mM 0.1061 mL 0.5303 mL 1.0606 mL 2.6515 mL
40 mM 0.0795 mL 0.3977 mL 0.7954 mL 1.9886 mL
50 mM 0.0636 mL 0.3182 mL 0.6364 mL 1.5909 mL
60 mM 0.0530 mL 0.2651 mL 0.5303 mL 1.3257 mL
80 mM 0.0398 mL 0.1989 mL 0.3977 mL 0.9943 mL
100 mM 0.0318 mL 0.1591 mL 0.3182 mL 0.7954 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的產(chǎn)品:

Your information is safe with us. * Required Fields.

   產(chǎn)品名稱(chēng)：

  

* 需求量：

* 客戶(hù)姓名：

 

* Email：

* 電話：

 

* 公司或機(jī)構(gòu)名稱(chēng)：

   留言給我們：

Bulk Inquiry

Inquiry Information

產(chǎn)品名稱(chēng)：
Pectolinarigenin
目錄號(hào)：
HY-N0493
需求量：