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  2. Epigenetics NF-κB Autophagy Anti-infection Apoptosis
  3. Histone Acetyltransferase Epigenetic Reader Domain Keap1-Nrf2 Autophagy Mitophagy Influenza Virus Ferroptosis
  4. Curcumin

Curcumin  (Synonyms: 姜黃素; Diferuloylmethane; Natural Yellow 3; Turmeric yellow)

目錄號: HY-N0005 純度: 98.16%
COA 產(chǎn)品使用指南 技術(shù)支持

Curcumin (Diferuloylmethane)，是一種天然酚類化合物，是乙酰轉(zhuǎn)移酶 p300/CREB 結(jié)合蛋白 特異性抑制劑，抑制組蛋白/非組蛋白的乙?；徒M蛋白乙酰轉(zhuǎn)移酶依賴的染色質(zhì)轉(zhuǎn)錄。Curcumin 對 NF-κb 和 MAPKs 有抑制作用，并具有抗炎、抗氧化、抗增殖和抗血管生成等多種藥理作用。Curcumin 通過 Keap1 半胱氨酸修飾誘導(dǎo) Nrf2 蛋白的穩(wěn)定。

MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報，我們不為任何個人用途提供產(chǎn)品和服務(wù)

Curcumin Chemical Structure

Curcumin Chemical Structure

CAS No. : 458-37-7

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規(guī)格 價格 是否有貨 數(shù)量
10 mM * 1 mL in DMSO ￥500
In-stock
100 mg ￥450
In-stock
500 mg ￥650
In-stock
1 g   詢價  
5 g   詢價  

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Customer Review

Other Forms of Curcumin:

MCE 顧客使用本產(chǎn)品發(fā)表的 82 篇科研文獻(xiàn)

WB
IF
Cell Viability Assay

    Curcumin purchased from MCE. Usage Cited in: Research Square Preprint. 2023 May 4.

    Curcumin (5, 10, 20, 40, 50 μM; 24 h) inhibits the viability of Hs578T cells in a concentration-dependent manner.

    Curcumin purchased from MCE. Usage Cited in: Research Square Preprint. 2023 May 4.

    Curcumin (20 μM; 24 h) significantly inhibits the protein expression of Fibronectin, mTOR, β-Catenin, p-Akt, Akt, N-Cadherin, p-S6, and S6 in Hs578T cells.

    Curcumin purchased from MCE. Usage Cited in: J Exp Clin Cancer Res. 2018 Oct 29;37(1):261.   [Abstract]

    A375 cells are incubated with DMSO, curcumin (25 μM), or apigenin (30 μM) for 4 h and then treated with IFN-γ (10 ng/mL) for indicated times. The levels of STAT1 phosphorylation at Tyr701 and total STAT1 are detected by Western blot analysis.

    Curcumin purchased from MCE. Usage Cited in: J Exp Clin Cancer Res. 2018 Oct 29;37(1):261.   [Abstract]

    A375, A2058, and RPMI-7951 cells were treated with DMSO (control), Curcumin (25 μM), or Apigenin (30 μM) for 24 h. Apigenin and Curcumin induce apoptosis in melanoma cells.

    Curcumin purchased from MCE. Usage Cited in: J Exp Clin Cancer Res. 2018 Oct 29;37(1):261.   [Abstract]

    The protein expression levels of cleaved PARP are detected from Curcumin and Apigenin-treated A375, A2058, and RPMI-7951 cell lysates compared to control samples using Western blotting analyses.

    Curcumin purchased from MCE. Usage Cited in: J Exp Clin Cancer Res. 2018 Oct 29;37(1):261.   [Abstract]

    Western analysis of PD-L1 expression in A375, A2058, and RPMI-7951 cells treated with IFN-γ, curcumin, or apigenin.

    Curcumin purchased from MCE. Usage Cited in: J Exp Clin Cancer Res. 2018 Oct 29;37(1):261.   [Abstract]

    A375 cells are incubated with DMSO, curcumin (25 μM), or apigenin (30 μM) for 4 h and then treated with IFN-γ (10 ng/mL) for indicated times. The levels of STAT1 phosphorylation at Tyr701 and total STAT1 are detected by Western blot analysis.

    Curcumin purchased from MCE. Usage Cited in: J Exp Clin Cancer Res. 2018 Oct 29;37(1):261.   [Abstract]

    A375 cells are incubated with DMSO, curcumin (25 μM), or apigenin (30 μM) for 4 h and then treated with IFN-γ (10 ng/mL) for indicated times. The levels of STAT1 phosphorylation at Tyr701 and total STAT1 are detected by Western blot analysis.

    Curcumin purchased from MCE. Usage Cited in: J Cell Biochem. 2019 Apr;120(4):6718-6728.  [Abstract]

    Western analysis of the expression of NLRP3, pro-casp-1, casp-1, pro-1β, IL-1β in the treatment with or without Curcumin, DMSO, MSU and Colchicine.

    Curcumin purchased from MCE. Usage Cited in: FASEB J. 2017 Sep;31(9):3800-3815.  [Abstract]

    Expression of CFTR after treatment with Curcumin (10 μM) for 3 d is assayed by Western blotting. TDSCs from WT mice are treated with Curcumin (10 μM) for 3 d and results show that CFTR expression is increased at the protein level.

    查看 Histone Acetyltransferase 亞型特異性產(chǎn)品:

    • 生物活性

    • 實驗參考方法

    • 純度 & 產(chǎn)品資料

    • 參考文獻(xiàn)

    生物活性

    Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.

    IC50 & Target

    CBP/p300

     

    細(xì)胞效力
    (Cellular Effect)
    Cell Line Type Value Description References
    4T1 IC50
    49.4 μM
    Compound: Curcumin
    Cytotoxicity against mouse 4T1 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against mouse 4T1 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    		[PMID: 27496212]
    A-431 IC50
    > 100 μM
    Compound: CUR
    Cytotoxicity against human A431 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
    Cytotoxicity against human A431 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
    		[PMID: 29605808]
    A549 IC50
    > 10 μM
    Compound: Curcumin
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    		[PMID: 29886021]
    A549 IC50
    0.2 μM
    Compound: 19
    Inhibition of microsomal PGES1 in ILbeta-stimulated human A549 cells using PGH2 as substrate preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis
    Inhibition of microsomal PGES1 in ILbeta-stimulated human A549 cells using PGH2 as substrate preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis
    		10.1039/C5MD00278H
    A549 IC50
    0.22 μM
    Compound: 4
    Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by HPLC analysis
    Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 preincubated for 15 mins by HPLC analysis
    		[PMID: 26588603]
    A549 IC50
    15.06 μM
    Compound: Curcumin
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    		[PMID: 27816267]
    A549 IC50
    17.3 μM
    Compound: 1, Curcumin, diferuloylmethane
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    		[PMID: 24280069]
    A549 IC50
    17.9 μM
    Compound: Curcumin
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    		[PMID: 30138803]
    A549 IC50
    18 μM
    Compound: Curc
    Cytotoxicity against human A549 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 28654265]
    A549 IC50
    23.54 μM
    Compound: Curcumin
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    		[PMID: 26873414]
    A549 IC50
    24.18 μM
    Compound: 4
    Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34020339]
    A549 IC50
    25.33 μM
    Compound: 1; CUR
    Cytotoxicity against human A549 Cells by MTT assay
    Cytotoxicity against human A549 Cells by MTT assay
    		[PMID: 31129455]
    A549 IC50
    27.8 μM
    Compound: CUR
    Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay
    		[PMID: 27886548]
    A549 IC50
    28 μM
    Compound: 1; CUR
    Cytotoxicity against human A549 Cells after 24 to 48 hrs by MTT assay
    Cytotoxicity against human A549 Cells after 24 to 48 hrs by MTT assay
    		[PMID: 31129455]
    A549 IC50
    32.5 μM
    Compound: 22
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
    		[PMID: 32172081]
    A549 IC50
    38.12 μM
    Compound: 2
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    		[PMID: 26891099]
    A549 IC50
    40.56 μM
    Compound: 2
    Inhibition of thioredoxin reductase in human A549 cells by DTNB dye based microplate spectrophotometry
    Inhibition of thioredoxin reductase in human A549 cells by DTNB dye based microplate spectrophotometry
    		[PMID: 26891099]
    A549 IC50
    43.9 μM
    Compound: CUR
    Cytotoxicity against human A549 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
    Cytotoxicity against human A549 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
    		[PMID: 29605808]
    A549 IC50
    52.3 μM
    Compound: 1; CUR
    Cytotoxicity against human A549 Cells after 24 hrs by MTT assay
    Cytotoxicity against human A549 Cells after 24 hrs by MTT assay
    		[PMID: 31129455]
    A549 IC50
    6.8 μM
    Compound: Curcumin
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 29655083]
    A549 IC50
    60.2 μM
    Compound: 18, Curcumin, Diferuloylmethane
    Cytotoxicity against human A549 cells after 24 hrs by MTT assay
    Cytotoxicity against human A549 cells after 24 hrs by MTT assay
    		[PMID: 26174555]
    A549/CDDP IC50
    32.39 μM
    Compound: 2
    Antiproliferative activity against human A549/CDDP cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549/CDDP cells after 72 hrs by MTT assay
    		[PMID: 26891099]
    A549/CDDP IC50
    39.42 μM
    Compound: 2
    Inhibition of thioredoxin reductase in human A549/CDDP cells by DTNB dye based microplate spectrophotometry
    Inhibition of thioredoxin reductase in human A549/CDDP cells by DTNB dye based microplate spectrophotometry
    		[PMID: 26891099]
    AGS IC50
    20.76 μM
    Compound: 1; CUR
    Cytotoxicity against human AGS Cells by MTT assay
    Cytotoxicity against human AGS Cells by MTT assay
    		[PMID: 31129455]
    BGC-823 IC50
    > 20 μM
    Compound: 1; CUR
    Antiproliferative activity against human BGC823 cells after 24 hrs by MTT assay
    Antiproliferative activity against human BGC823 cells after 24 hrs by MTT assay
    		[PMID: 31129455]
    BGC-823 IC50
    19.5 μM
    Compound: Curcumin
    Cytotoxicity against human BGC823 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human BGC823 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    		[PMID: 29288946]
    Bone marrow cell IC50
    7.5 μM
    Compound: Curcumin
    Inhibition of RANKL-induced osteoclast differentiation in ICR mouse bone marrow cells after 48 hrs by TRAP assay
    Inhibition of RANKL-induced osteoclast differentiation in ICR mouse bone marrow cells after 48 hrs by TRAP assay
    		[PMID: 26923696]
    BT-474 IC50
    30.14 μM
    Compound: Curcumin
    Antiproliferative activity against HER2 positive human BT474 cells after 24 hrs by MTT assay
    Antiproliferative activity against HER2 positive human BT474 cells after 24 hrs by MTT assay
    		[PMID: 28319780]
    BT-549 IC50
    24.93 μM
    Compound: Curcumin
    Antiproliferative activity against human BT549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human BT549 cells after 48 hrs by MTT assay
    		[PMID: 28038323]
    BV-2 IC50
    0.5 μM
    Compound: Curcumin
    Inhibition of NO production in LPS-stimulated mouse BV-2 cells preincubated with compound for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent-based assay
    Inhibition of NO production in LPS-stimulated mouse BV-2 cells preincubated with compound for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent-based assay
    		[PMID: 33454546]
    BV-2 IC50
    0.5 μM
    Compound: Curcumin
    Inhibition of LPS-induced NO production in mouse BV-2 cells by MTT assay
    Inhibition of LPS-induced NO production in mouse BV-2 cells by MTT assay
    		[PMID: 33454546]
    BV-2 IC50
    0.52 μM
    Compound: Curcumin
    Inhibition of LPS-induced NO production in mouse BV2 cells assessed as reduction in nitrite level pretreated for 24 hrs before LPS treatment for additional 24 hrs by Griess reaction method
    Inhibition of LPS-induced NO production in mouse BV2 cells assessed as reduction in nitrite level pretreated for 24 hrs before LPS treatment for additional 24 hrs by Griess reaction method
    		[PMID: 26859776]
    BV-2 IC50
    1.42 μM
    Compound: Curcumin
    Inhibition of LPS-induced nitric oxide production in mouse BV2 cells pretreated for 1 hr before LPS stimulation measured after 24 hrs by Griess assay
    Inhibition of LPS-induced nitric oxide production in mouse BV2 cells pretreated for 1 hr before LPS stimulation measured after 24 hrs by Griess assay
    		[PMID: 27592135]
    BV-2 IC50
    2.2 μM
    Compound: Curcumin
    Inhibition of Src in mouse BV2 cells assessed as suppression of LPS-induced NO release preincubated for 1 hr followed by LPS addition measured after 24 hrs by Griess assay
    Inhibition of Src in mouse BV2 cells assessed as suppression of LPS-induced NO release preincubated for 1 hr followed by LPS addition measured after 24 hrs by Griess assay
    		[PMID: 27617803]
    BV-2 IC50
    2.36 μM
    Compound: Curcumin
    Inhibition of LPS-induced nitric oxide production in mouse BV2 cells pretreated for 24 hrs followed by LPS-stimulation after 24 hrs by Griess assay
    Inhibition of LPS-induced nitric oxide production in mouse BV2 cells pretreated for 24 hrs followed by LPS-stimulation after 24 hrs by Griess assay
    		[PMID: 28032759]
    BV-2 IC50
    2.69 μM
    Compound: Curcumin
    Antiinflammatory activity in mouse BV2 cells assessed as reduction in LPS-induced nitric oxide production by colorimetric assay
    Antiinflammatory activity in mouse BV2 cells assessed as reduction in LPS-induced nitric oxide production by colorimetric assay
    		[PMID: 36346918]
    BV-2 IC50
    3 μM
    Compound: Curcumin
    Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO-production preincubated for 1 hr followed by LPS stimulation and measured after 24 hrs by microplate reader based colorimetric assay
    Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO-production preincubated for 1 hr followed by LPS stimulation and measured after 24 hrs by microplate reader based colorimetric assay
    		[PMID: 34185528]
    BV-2 IC50
    4 μM
    Compound: Curcumin
    Antiinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by griess assay
    Antiinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by griess assay
    		[PMID: 29035525]
    BV-2 IC50
    4.5 μM
    Compound: Curcumin
    Inhibition of LPS-induced nitric oxide production in mouse BV2 cells pretreated for 30 mins followed by LPS-stimulation after 24 hrs by Griess assay
    Inhibition of LPS-induced nitric oxide production in mouse BV2 cells pretreated for 30 mins followed by LPS-stimulation after 24 hrs by Griess assay
    		[PMID: 28055210]
    BV-2 IC50
    4.77 μM
    Compound: Curcumin
    Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
    Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
    		[PMID: 27228227]
    BV-2 IC50
    6 μM
    Compound: Curcumin
    Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production pretreated for 15 mins followed by LPS-stimulation measured after 24 hrs by colorimetric method
    Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production pretreated for 15 mins followed by LPS-stimulation measured after 24 hrs by colorimetric method
    		[PMID: 28514148]
    BXPC-3 IC50
    29 μM
    Compound: Curc
    Cytotoxicity against human BxPC3 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human BxPC3 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 28654265]
    Caco-2 IC50
    > 25 μM
    Compound: 1a
    Growth inhibition of undifferentiated human Caco2 cells assessed as mitochondrial activity measured after 72 hrs by MTT assay
    Growth inhibition of undifferentiated human Caco2 cells assessed as mitochondrial activity measured after 72 hrs by MTT assay
    		[PMID: 27521589]
    Caco-2 IC50
    > 25 μM
    Compound: 1a
    Growth inhibition of differentiated human Caco2 cells assessed as mitochondrial activity measured after 72 hrs by MTT assay
    Growth inhibition of differentiated human Caco2 cells assessed as mitochondrial activity measured after 72 hrs by MTT assay
    		[PMID: 27521589]
    Caco-2 IC50
    > 25 μM
    Compound: 1a
    Growth inhibition of undifferentiated human Caco2 cells measured after 72 hrs by SRB assay
    Growth inhibition of undifferentiated human Caco2 cells measured after 72 hrs by SRB assay
    		[PMID: 27521589]
    Caco-2 IC50
    > 25 μM
    Compound: 1a
    Growth inhibition of differentiated human Caco2 cells measured after 72 hrs by SRB assay
    Growth inhibition of differentiated human Caco2 cells measured after 72 hrs by SRB assay
    		[PMID: 27521589]
    Caco-2 IC50
    28 μM
    Compound: 1; CUR
    Cytotoxicity against human Caco2 Cells after 72 hrs by MTT assay
    Cytotoxicity against human Caco2 Cells after 72 hrs by MTT assay
    		[PMID: 31129455]
    Caco-2 IC50
    38.3 μM
    Compound: 1a
    Cytotoxicity against human Caco2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human Caco2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 27843113]
    CCD-18Co GI50
    7.2 μg/mL
    Compound: Curc
    Cytotoxicity against human CCD-18Co cells assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo luminescent cell viability
    Cytotoxicity against human CCD-18Co cells assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo luminescent cell viability
    		[PMID: 31767266]
    CCD-841CoN GI50
    58.6 μM
    Compound: 5
    Cytotoxicity against human CRL1790 cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human CRL1790 cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay
    		[PMID: 28716495]
    CHO-K1 IC50
    > 25 μM
    Compound: 1a
    Growth inhibition of CHOK1 cells measured after 72 hrs by SRB assay
    Growth inhibition of CHOK1 cells measured after 72 hrs by SRB assay
    		[PMID: 27521589]
    CHO-K1 IC50
    21.3 μM
    Compound: 1; CUR
    Cytotoxicity against human CHOK1 Cells after 72 hrs by MTT assay
    Cytotoxicity against human CHOK1 Cells after 72 hrs by MTT assay
    		[PMID: 31129455]
    CHO-K1 IC50
    42 μM
    Compound: 1a
    Cytotoxicity against CHOK1 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against CHOK1 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 27843113]
    CHO-K1 IC50
    7.5 μM
    Compound: 1a
    Growth inhibition of CHOK1 cells assessed as mitochondrial activity measured after 72 hrs by MTT assay
    Growth inhibition of CHOK1 cells assessed as mitochondrial activity measured after 72 hrs by MTT assay
    		[PMID: 27521589]
    COLO 201 IC50
    18 μM
    Compound: Curc
    Cytotoxicity against human COLO201 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human COLO201 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 28654265]
    COLO 205 GI50
    12.7 μg/mL
    Compound: Curc
    Growth inhibition of human COLO205 cells incubated for 72 hrs by CellTiter-Glo luminescent cell viability
    Growth inhibition of human COLO205 cells incubated for 72 hrs by CellTiter-Glo luminescent cell viability
    		[PMID: 31767266]
    Colon 26 IC50
    30.34 μM
    Compound: CU
    Cytotoxicity against mouse Colon 26 cells after 4 hrs by MTT assay
    Cytotoxicity against mouse Colon 26 cells after 4 hrs by MTT assay
    		[PMID: 31336310]
    CT26 IC50
    7.7 μM
    Compound: CUR
    Cytotoxicity against mouse CT26 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
    Cytotoxicity against mouse CT26 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
    		[PMID: 26318057]
    CWR22R GI50
    14.3 μg/mL
    Compound: Curc
    Growth inhibition of human 22Rv1 cells incubated for 48 hrs by MTS assay
    Growth inhibition of human 22Rv1 cells incubated for 48 hrs by MTS assay
    		[PMID: 31767266]
    DLD-1 IC50
    > 40 μM
    Compound: CUR
    Cytotoxicity against human DLD1 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
    Cytotoxicity against human DLD1 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
    		[PMID: 29605808]
    DU-145 IC50
    26.23 μM
    Compound: 1
    Antiproliferative activity against androgen-insensitive human DU145 cells assessed as decrease in cell viability after 3 days by WST assay
    Antiproliferative activity against androgen-insensitive human DU145 cells assessed as decrease in cell viability after 3 days by WST assay
    		[PMID: 30121214]
    DU-145 IC50
    26.23 μM
    Compound: Curcumin
    Antiproliferative activity against human DU145 cells assessed as decrease in cell viability after 3 days by WST assay
    Antiproliferative activity against human DU145 cells assessed as decrease in cell viability after 3 days by WST assay
    		[PMID: 28601720]
    DU-145 IC50
    26.23 μM
    Compound: 1
    Antiproliferative activity against human DU145 cells after 3 days by WST-1 assay
    Antiproliferative activity against human DU145 cells after 3 days by WST-1 assay
    		[PMID: 28388523]
    DU-145 IC50
    26.23 μM
    Compound: 1a; Curcumin
    Antiproliferative activity against human DU145 cells assessed as inhibition of cell viability after 3 days by WST-1 assay
    Antiproliferative activity against human DU145 cells assessed as inhibition of cell viability after 3 days by WST-1 assay
    		[PMID: 26827161]
    DU-145 IC50
    26.23 μM
    Compound: Curcumin
    Antiproliferative activity against human DU145 cells after 3 days by WST or trypan blue assay
    Antiproliferative activity against human DU145 cells after 3 days by WST or trypan blue assay
    		[PMID: 27543391]
    DU-145 IC50
    28.41 μM
    Compound: Curcumin
    Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
    Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
    		[PMID: 28038323]
    DU-145 IC50
    33.12 μM
    Compound: Curcumin
    Cytotoxicity against human DU145 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    Cytotoxicity against human DU145 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    		[PMID: 29174816]
    DU-145 IC50
    33.15 μM
    Compound: Curcumin
    Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 29429834]
    DU-145 IC50
    41 μM
    Compound: Curcumin
    Cytotoxicity against human DU145 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human DU145 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    		[PMID: 27496212]
    DU-145 IC50
    44.71 μM
    Compound: Curcumin
    Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
    Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
    		[PMID: 27816267]
    EA.hy 926 IC50
    > 25 μM
    Compound: 1a
    Growth inhibition of human EAhy926 cells assessed as mitochondrial activity measured after 72 hrs by MTT assay
    Growth inhibition of human EAhy926 cells assessed as mitochondrial activity measured after 72 hrs by MTT assay
    		[PMID: 27521589]
    EA.hy 926 IC50
    > 25 μM
    Compound: 1a
    Growth inhibition of human EAhy926 cells measured after 72 hrs by SRB assay
    Growth inhibition of human EAhy926 cells measured after 72 hrs by SRB assay
    		[PMID: 27521589]
    EA.hy 926 IC50
    20 μM
    Compound: 1; CUR
    Cytotoxicity against human EAhy926 Cells after 72 hrs by MTT assay
    Cytotoxicity against human EAhy926 Cells after 72 hrs by MTT assay
    		[PMID: 31129455]
    EA.hy 926 IC50
    24.6 μM
    Compound: 1a
    Cytotoxicity against human EAhy926 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human EAhy926 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 27843113]
    GES1 IC50
    27.89 μM
    Compound: CUR
    Cytotoxicity against human GES-1 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
    Cytotoxicity against human GES-1 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
    		[PMID: 26318057]
    HCT-116 IC50
    10 μM
    Compound: Curcumin
    Inhibition of chymotrypsin-like activity of human 26S proteasome in human HCT-116 cells assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as substrate preincubated for 24 hrs followed by addition of substrate and measured after 2 hrs by fluorometr
    Inhibition of chymotrypsin-like activity of human 26S proteasome in human HCT-116 cells assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as substrate preincubated for 24 hrs followed by addition of substrate and measured after 2 hrs by fluorometr
    		[PMID: 30776692]
    HCT-116 IC50
    10.5 μM
    Compound: Curcumin
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31326241]
    HCT-116 IC50
    10.91 μM
    Compound: Curcumin
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    		[PMID: 29886021]
    HCT-116 IC50
    13.77 μM
    Compound: Curcumin
    Antiproliferative activity against human HCT116 cells up to 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells up to 72 hrs by MTT assay
    		[PMID: 28319780]
    HCT-116 IC50
    2.4 μM
    Compound: 3
    Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay
    		[PMID: 32273215]
    HCT-116 IC50
    2.67 μM
    Compound: 3
    Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
    		[PMID: 32273215]
    HCT-116 GI50
    3.5 μM
    Compound: 5
    Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    		[PMID: 28716495]
    HCT-116 IC50
    3.83 μM
    Compound: 3
    Antiproliferative activity against human HCT116 cells incubated for 24 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells incubated for 24 hrs by MTT assay
    		[PMID: 32273215]
    HCT-116 IC50
    34.7 μM
    Compound: Curcumin
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 32731188]
    HCT-116 IC50
    50 μM
    Compound: Curcumin
    Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 27318975]
    HCT-116 IC50
    50 μM
    Compound: Curcumin
    Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 26810315]
    HCT-116 IC50
    50 μM
    Compound: Curcumin
    Antiproliferative activity against human HCT116 cells after 36 hrs by XTT assay
    Antiproliferative activity against human HCT116 cells after 36 hrs by XTT assay
    		[PMID: 29886021]
    HEK293 IC50
    > 400 μM
    Compound: Curcumin
    Cytotoxicity against human HEK293 cells after 48 hrs by MTT assay
    Cytotoxicity against human HEK293 cells after 48 hrs by MTT assay
    		[PMID: 26783179]
    HEK293 CC50
    5.56 μM
    Compound: 1
    Cytotoxicity against human HEK293 cells assessed as reduction in cell viability at 20 uM measured after 48 hrs by resazurin reagent based multilabel reader analysis
    Cytotoxicity against human HEK293 cells assessed as reduction in cell viability at 20 uM measured after 48 hrs by resazurin reagent based multilabel reader analysis
    		[PMID: 36608774]
    HEK293 IC50
    7.7 μg/mL
    Compound: Curc
    Inhibition of TNFalpha-induced NFkappaB activation in human HEK293 cells preincubated for 16 hrs followed by TNFalpha addition and measured after 6 hrs by luminescence based assay
    Inhibition of TNFalpha-induced NFkappaB activation in human HEK293 cells preincubated for 16 hrs followed by TNFalpha addition and measured after 6 hrs by luminescence based assay
    		[PMID: 31767266]
    HEK293 IC50
    94.1 μM
    Compound: Curcumin
    Cytotoxicity against human HEK293 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human HEK293 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    		[PMID: 27496212]
    HEK-293T IC50
    > 400 μM
    Compound: Curcumin
    Cytotoxicity against HEK293T cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against HEK293T cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 28797797]
    HeLa IC50
    12.11 μM
    Compound: 1a; Curcumin
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell viability after 3 days by WST-1 assay
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell viability after 3 days by WST-1 assay
    		[PMID: 26827161]
    HeLa IC50
    187 μM
    Compound: 4
    Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assay
    Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assay
    		[PMID: 26588603]
    HeLa IC50
    21.8 μM
    Compound: 1
    Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs
    Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs
    		[PMID: 26705144]
    HeLa IC50
    25.41 μM
    Compound: Curcumin
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    		[PMID: 28038323]
    HeLa IC50
    3.56 μM
    Compound: 3
    Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
    		[PMID: 32273215]
    HeLa IC50
    3.57 μM
    Compound: 3
    Antiproliferative activity against human HeLa cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells incubated for 48 hrs by MTT assay
    		[PMID: 32273215]
    HeLa IC50
    31.89 μM
    Compound: Curcumin
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		[PMID: 29421568]
    HeLa IC50
    32.4 μM
    Compound: 9
    Growth inhibition of human HeLa cells measured after 48 hrs by MTT assay
    Growth inhibition of human HeLa cells measured after 48 hrs by MTT assay
    		[PMID: 34669417]
    HeLa IC50
    5.39 μM
    Compound: 3
    Antiproliferative activity against human HeLa cells incubated for 24 hrs by MTT assay
    Antiproliferative activity against human HeLa cells incubated for 24 hrs by MTT assay
    		[PMID: 32273215]
    HeLa IC50
    50 μM
    Compound: Curcumin
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 27318975]
    HeLa IC50
    51.87 μM
    Compound: Curcumin
    Cytotoxicity against human HeLa cells by MTT assay
    Cytotoxicity against human HeLa cells by MTT assay
    		[PMID: 26873414]
    HepG2 IC50
    10 μM
    Compound: Curcumin-I
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		[PMID: 29798827]
    HepG2 IC50
    13.78 μM
    Compound: Curcumin
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		[PMID: 29421568]
    HepG2 IC50
    16.01 μM
    Compound: Curcumin
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		[PMID: 29909338]
    HepG2 IC50
    17.3 μM
    Compound: Curcumin
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay
    		[PMID: 34450496]
    HepG2 IC50
    17.37 μM
    Compound: Curcumin
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
    		[PMID: 30771605]
    HepG2 IC50
    20.3 μM
    Compound: 1; CUR
    Cytotoxicity against human HepG2 Cells after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 Cells after 72 hrs by MTT assay
    		[PMID: 31129455]
    HepG2 IC50
    27.23 μM
    Compound: 4
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34020339]
    HepG2 IC50
    4.43 μM
    Compound: Curcumin
    Cytotoxicity activity against human HepG2 cells by MTT assay
    Cytotoxicity activity against human HepG2 cells by MTT assay
    		[PMID: 26873414]
    HepG2 IC50
    50 μM
    Compound: Curcumin
    Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 26810315]
    HepG2 IC50
    52.3 μM
    Compound: curcumin
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 26894841]
    HepG2 IC50
    72.7 μM
    Compound: 1a
    Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 27843113]
    HepG2 IC50
    9.44 μM
    Compound: 1; CUR
    Cytotoxicity against human HepG2 Cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 Cells after 48 hrs by MTT assay
    		[PMID: 31129455]
    Hs-578T IC50
    55.45 μM
    Compound: Curcumin
    Antiproliferative activity against human Hs578T cells after 24 hrs by MTT assay
    Antiproliferative activity against human Hs578T cells after 24 hrs by MTT assay
    		[PMID: 28319780]
    HT-1080 IC50
    13.1 μM
    Compound: Curcumin
    Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
    Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
    		[PMID: 30138803]
    HT-22 IC50
    52.4 μM
    Compound: 38
    Cytotoxicity against mouse HT-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
    Cytotoxicity against mouse HT-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
    		[PMID: 36876904]
    HT-29 IC50
    > 25 μM
    Compound: 1a
    Growth inhibition of human HT-29 cells assessed as mitochondrial activity measured after 72 hrs by MTT assay
    Growth inhibition of human HT-29 cells assessed as mitochondrial activity measured after 72 hrs by MTT assay
    		[PMID: 27521589]
    HT-29 IC50
    > 25 μM
    Compound: 1a
    Growth inhibition of human HT-29 cells measured after 72 hrs by SRB assay
    Growth inhibition of human HT-29 cells measured after 72 hrs by SRB assay
    		[PMID: 27521589]
    HT-29 IC50
    14 μM
    Compound: Curc
    Cytotoxicity against human HT-29 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HT-29 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 28654265]
    HT-29 IC50
    20.73 μM
    Compound: CU
    Cytotoxicity against human HT-29 cells after 4 hrs by MTT assay
    Cytotoxicity against human HT-29 cells after 4 hrs by MTT assay
    		[PMID: 31336310]
    HT-29 IC50
    23.4 μM
    Compound: 1; CUR
    Cytotoxicity against human HT-29 Cells after 72 hrs by MTT assay
    Cytotoxicity against human HT-29 Cells after 72 hrs by MTT assay
    		[PMID: 31129455]
    HT-29 IC50
    51.7 μM
    Compound: 1a
    Cytotoxicity against human HT-29 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HT-29 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 27843113]
    Huh-7 IC50
    48 μM
    Compound: Curcumin
    Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay
    Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay
    		[PMID: 26783179]
    Jurkat IC50
    4.29 μM
    Compound: 1, Curcumin, diferuloylmethane
    Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
    Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
    		[PMID: 24280069]
    K562 GI50
    19.67 μM
    Compound: 1
    Inhibition of P-gp in doxorubicin resistant human K562 cells assessed as reduction in cell viability measured after 48 hrs by Presto blue assay
    Inhibition of P-gp in doxorubicin resistant human K562 cells assessed as reduction in cell viability measured after 48 hrs by Presto blue assay
    		[PMID: 27908756]
    K562 GI50
    21.67 μM
    Compound: 1
    Antiproliferative activity against human K562 cells measured after 48 hrs by Presto blue assay
    Antiproliferative activity against human K562 cells measured after 48 hrs by Presto blue assay
    		[PMID: 27908756]
    K562 IC50
    23.12 μM
    Compound: Curcumin
    Cytotoxicity against human K562 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human K562 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		[PMID: 29421568]
    K562 IC50
    36 μM
    Compound: 1; CUR
    Cytotoxicity against human K562 Cells after 24 to 48 hrs by MTT assay
    Cytotoxicity against human K562 Cells after 24 to 48 hrs by MTT assay
    		[PMID: 31129455]
    K562 IC50
    46.76 μM
    Compound: 4
    Cytotoxicity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34020339]
    KBM5 IC50
    3.84 μM
    Compound: 1, Curcumin, diferuloylmethane
    Antiproliferative activity against human KBM5 cells after 72 hrs by MTT assay
    Antiproliferative activity against human KBM5 cells after 72 hrs by MTT assay
    		[PMID: 24280069]
    KM12 IC50
    16 μM
    Compound: CU
    Cytotoxicity against human KM12 cells after 4 hrs by MTT assay
    Cytotoxicity against human KM12 cells after 4 hrs by MTT assay
    		[PMID: 31336310]
    L02 IC50
    22.69 μM
    Compound: Curcumin
    Cytotoxicity against human LO2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
    Cytotoxicity against human LO2 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
    		[PMID: 30771605]
    L02 IC50
    23.87 μM
    Compound: Curcumin
    Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		[PMID: 29909338]
    L02 IC50
    25.67 μM
    Compound: Curcumin
    Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		[PMID: 29421568]
    L02 IC50
    7.2 μM
    Compound: Curcumin
    Cytotoxicity against human HL7702 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human HL7702 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 29655083]
    Lewis lung carcinoma cell line IC50
    24.7 μM
    Compound: CUR
    Cytotoxicity against mouse LLC cells measured after 72 hrs by MTT assay
    Cytotoxicity against mouse LLC cells measured after 72 hrs by MTT assay
    		[PMID: 27886548]
    LN-229 IC50
    15 μM
    Compound: Curc
    Cytotoxicity against human LN229 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human LN229 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 28654265]
    LNCaP IC50
    13.61 μM
    Compound: 1
    Antiproliferative activity against androgen-sensitive human LNCAP cells assessed as decrease in cell viability after 3 days by WST assay
    Antiproliferative activity against androgen-sensitive human LNCAP cells assessed as decrease in cell viability after 3 days by WST assay
    		[PMID: 30121214]
    LNCaP IC50
    13.61 μM
    Compound: Curcumin
    Antiproliferative activity against human LNCAP cells assessed as decrease in cell viability after 3 days by WST assay
    Antiproliferative activity against human LNCAP cells assessed as decrease in cell viability after 3 days by WST assay
    		[PMID: 28601720]
    LNCaP IC50
    13.61 μM
    Compound: 1
    Antiproliferative activity against human LNCAP cells after 3 days by WST-1 assay
    Antiproliferative activity against human LNCAP cells after 3 days by WST-1 assay
    		[PMID: 28388523]
    LNCaP IC50
    13.61 μM
    Compound: 1a; Curcumin
    Antiproliferative activity against human LNCAP cells assessed as inhibition of cell viability after 3 days by WST-1 assay
    Antiproliferative activity against human LNCAP cells assessed as inhibition of cell viability after 3 days by WST-1 assay
    		[PMID: 26827161]
    LNCaP IC50
    13.61 μM
    Compound: Curcumin
    Antiproliferative activity against human LNCAP cells after 3 days by WST or trypan blue assay
    Antiproliferative activity against human LNCAP cells after 3 days by WST or trypan blue assay
    		[PMID: 27543391]
    LoVo GI50
    4.3 μg/mL
    Compound: Curc
    Growth inhibition of human LoVo cells incubated for 72 hrs by CellTiter-Glo luminescent cell viability
    Growth inhibition of human LoVo cells incubated for 72 hrs by CellTiter-Glo luminescent cell viability
    		[PMID: 31767266]
    MCF7 IC50
    13.7 μM
    Compound: Curcumin
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 32731188]
    MCF7 IC50
    2.03 μM
    Compound: 3
    Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay
    		[PMID: 32273215]
    MCF7 IC50
    2.08 μM
    Compound: 3
    Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells incubated for 48 hrs by MTT assay
    		[PMID: 32273215]
    MCF7 IC50
    2.94 μM
    Compound: 3
    Antiproliferative activity against human MCF7 cells incubated for 24 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells incubated for 24 hrs by MTT assay
    		[PMID: 32273215]
    MCF7 IC50
    22.1 μM
    Compound: CUR
    Cytotoxicity against human MCF7 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells preincubated for 4 hrs followed by incubation in compound free media for 24 hrs by MTT assay
    		[PMID: 29605808]
    MCF7 IC50
    29.3 μM
    Compound: Curcumin
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition and measured after 72 hrs by SRB assay
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition and measured after 72 hrs by SRB assay
    		[PMID: 34000484]
    MCF7 IC50
    32.2 μM
    Compound: 18, Curcumin, Diferuloylmethane
    Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay
    		[PMID: 26174555]
    MCF7 IC50
    41.9 μM
    Compound: 50
    Anticancer activity against human MCF7 cells assessed as inhibition of cell viability incubated for 48 hrs by CCK-8 assay
    Anticancer activity against human MCF7 cells assessed as inhibition of cell viability incubated for 48 hrs by CCK-8 assay
    		[PMID: 36332549]
    MCF7 IC50
    42.89 μM
    Compound: Curcumin
    Antiproliferative activity against ER/PR positive human MCF7 cells after 24 hrs by MTT assay
    Antiproliferative activity against ER/PR positive human MCF7 cells after 24 hrs by MTT assay
    		[PMID: 28319780]
    MCF7 IC50
    46.25 μM
    Compound: Curcumin
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    		[PMID: 26873414]
    MCF7 IC50
    61.71 μM
    Compound: Curcumin
    Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs in presence of resveratrol by MTS assay
    Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs in presence of resveratrol by MTS assay
    		[PMID: 32485531]
    MCF7 IC50
    68.25 μM
    Compound: Curcumin
    Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by MTS assay
    Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by MTS assay
    		[PMID: 32485531]
    MCF7 IC50
    68.25 μM
    Compound: 1; CUR
    Cytotoxicity against human MCF7 Cells after 48 hrs by MTS assay
    Cytotoxicity against human MCF7 Cells after 48 hrs by MTS assay
    		[PMID: 31129455]
    MCF7 IC50
    83.1 μM
    Compound: Curcumin
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    		[PMID: 27496212]
    MCF7 IC50
    9.28 μM
    Compound: 1; CUR
    Cytotoxicity against human MCF7 Cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 Cells after 48 hrs by MTT assay
    		[PMID: 31129455]
    MCF7 IC50
    9.8 μM
    Compound: Curcumin
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    		[PMID: 30138803]
    MCF7R IC50
    26.2 μM
    Compound: Curcumin
    Cytotoxicity against human MCF7R cells assessed as cell growth inhibition and by MTT assay
    Cytotoxicity against human MCF7R cells assessed as cell growth inhibition and by MTT assay
    		[PMID: 34000484]
    MDA-MB-157 IC50
    40.38 μM
    Compound: Curcumin
    Antiproliferative activity against human MDA-MB-157 cells after 24 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-157 cells after 24 hrs by MTT assay
    		[PMID: 28319780]
    MDA-MB-231 IC50
    > 10 μM
    Compound: Curcumin
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 29886021]
    MDA-MB-231 IC50
    11.45 μM
    Compound: 1; CUR
    Anticancer activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    Anticancer activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    		[PMID: 31129455]
    MDA-MB-231 IC50
    12 μM
    Compound: Curc
    Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 28654265]
    MDA-MB-231 IC50
    15.81 μM
    Compound: Curcumin
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 28038323]
    MDA-MB-231 IC50
    16.23 μM
    Compound: Curcumin
    Antiproliferative activity against human MDA-MB-231 cells up to 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells up to 72 hrs by MTT assay
    		[PMID: 28319780]
    MDA-MB-231 IC50
    24.54 μM
    Compound: Curcumin
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    		[PMID: 27816267]
    MDA-MB-231 IC50
    31.39 μM
    Compound: 4
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 34020339]
    MDA-MB-231 IC50
    53.51 μM
    Compound: 50
    Anticancer activity against human MDA-MB-231 cells assessed as inhibition of cell viability incubated for 48 hrs by CCK-8 assay
    Anticancer activity against human MDA-MB-231 cells assessed as inhibition of cell viability incubated for 48 hrs by CCK-8 assay
    		[PMID: 36332549]
    MDA-MB-231 IC50
    75.3 μM
    Compound: Curcumin
    Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    		[PMID: 27496212]
    MDA-MB-453 IC50
    32.4 μM
    Compound: Curcumin
    Antiproliferative activity against HER2 positive human MDA-MB-453 cells after 24 hrs by MTT assay
    Antiproliferative activity against HER2 positive human MDA-MB-453 cells after 24 hrs by MTT assay
    		[PMID: 28319780]
    MDA-MB-468 IC50
    42.89 μM
    Compound: Curcumin
    Antiproliferative activity against human MDA-MB-468 cells after 24 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-468 cells after 24 hrs by MTT assay
    		[PMID: 28319780]
    MDA-MB-468 IC50
    58.55 μM
    Compound: Curcumin
    Antiproliferative activity against doxorubicin-resistant human MDA-MB-468 cells after 24 hrs by MTT assay
    Antiproliferative activity against doxorubicin-resistant human MDA-MB-468 cells after 24 hrs by MTT assay
    		[PMID: 28319780]
    MDCK CC50
    48.3 μM
    Compound: Curcumin
    Cytotoxicity against MDCK cells assessed as decrease in cell viability after 40 hrs by CellTiter-Glo assay
    Cytotoxicity against MDCK cells assessed as decrease in cell viability after 40 hrs by CellTiter-Glo assay
    		10.1039/C6MD00292G
    MDCK CC50
    48.3 μM
    Compound: Curcumin
    Cytotoxicity against MDCK cells assessed as reduction in cell viability after 40 hrs by CellTiter-Glo assay
    Cytotoxicity against MDCK cells assessed as reduction in cell viability after 40 hrs by CellTiter-Glo assay
    		[PMID: 30108865]
    MGC-803 IC50
    > 20 μM
    Compound: 1; CUR
    Antiproliferative activity against human MGC803 cells after 24 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 24 hrs by MTT assay
    		[PMID: 31129455]
    MGC-803 IC50
    31.39 μM
    Compound: CUR
    Cytotoxicity against human MGC803 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
    Cytotoxicity against human MGC803 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
    		[PMID: 26318057]
    N2a IC50
    22.6 μM
    Compound: Curcumin
    Neurotoxicity in mouse N2a cells assessed as cell viability for 24 hrs by MTT assay
    Neurotoxicity in mouse N2a cells assessed as cell viability for 24 hrs by MTT assay
    		[PMID: 34391121]
    NCI-H1650 IC50
    20.5 μM
    Compound: Curcumin
    Cytotoxicity against human NCI-H1650 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human NCI-H1650 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 29655083]
    NCI-H1650 IC50
    20.7 μM
    Compound: CUR
    Cytotoxicity against human NCI-H1650 cells measured after 72 hrs by MTT assay
    Cytotoxicity against human NCI-H1650 cells measured after 72 hrs by MTT assay
    		[PMID: 27886548]
    NCI-H1975 IC50
    1.4 μM
    Compound: Curcumin
    Cytotoxicity against human NCI-H1975 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human NCI-H1975 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 29655083]
    NCI-H460 IC50
    15 μM
    Compound: Curc
    Cytotoxicity against human NCI-H460 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 28654265]
    NCI-H460 IC50
    17.11 μM
    Compound: Curcumin
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 29429834]
    NCI-H460 IC50
    17.14 μM
    Compound: Curcumin
    Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    		[PMID: 29174816]
    NCI-H460 IC50
    20.3 μM
    Compound: Curcumin
    Cytotoxicity against human NCI-H460 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    		[PMID: 29288946]
    NCI-H460 GI50
    27.3 μM
    Compound: 1
    Antiproliferative activity against human NCI-H460 cells measured after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human NCI-H460 cells measured after 48 hrs by sulforhodamine B assay
    		[PMID: 27908756]
    NCI-H460 IC50
    5.3 μM
    Compound: 22
    Antiproliferative activity against human NCI-H460 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
    Antiproliferative activity against human NCI-H460 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
    		[PMID: 32172081]
    NCI-H460 IC50
    8.5 μM
    Compound: Curcumin
    Cytotoxicity against human H460 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human H460 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    		[PMID: 29655083]
    NCI-H460 IC50
    82.5 μM
    Compound: 18, Curcumin, Diferuloylmethane
    Cytotoxicity against human H460 cells after 24 hrs by MTT assay
    Cytotoxicity against human H460 cells after 24 hrs by MTT assay
    		[PMID: 26174555]
    NHDF IC50
    24.1 μM
    Compound: Curcumin
    Cytotoxicity against NHDF after 72 hrs by MTT assay
    Cytotoxicity against NHDF after 72 hrs by MTT assay
    		[PMID: 30138803]
    NIH3T3 IC50
    9.51 μM
    Compound: 1; CUR
    Cytotoxicity against mouse 3T3 Cells after 48 hrs by MTT assay
    Cytotoxicity against mouse 3T3 Cells after 48 hrs by MTT assay
    		[PMID: 31129455]
    PANC-1 IC50
    53 μM
    Compound: Curc
    Cytotoxicity against human PANC1 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human PANC1 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 28654265]
    PC-12 CC50
    42 μM
    Compound: 1; CUR
    Cytotoxicity against rat PC12 cells measured after 24 hrs by WST8/PMS assay
    Cytotoxicity against rat PC12 cells measured after 24 hrs by WST8/PMS assay
    		[PMID: 31262559]
    PC-12 CC50
    44 μM
    Compound: Curcumin
    Cytotoxicity against rat PC12 cells assessed as reduction in cell viability incubated for 24 hrs by WST-8 assay
    Cytotoxicity against rat PC12 cells assessed as reduction in cell viability incubated for 24 hrs by WST-8 assay
    		[PMID: 33611188]
    PC-3 IC50
    12.22 μM
    Compound: Curcumin
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    		[PMID: 28038323]
    PC-3 GI50
    13.8 μg/mL
    Compound: Curc
    Growth inhibition of human PC3 cells incubated for 48 hrs by MTS assay
    Growth inhibition of human PC3 cells incubated for 48 hrs by MTS assay
    		[PMID: 31767266]
    PC-3 IC50
    18.65 μM
    Compound: Curcumin
    Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    		[PMID: 29429834]
    PC-3 IC50
    18.71 μM
    Compound: Curcumin
    Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    		[PMID: 29174816]
    PC-3 IC50
    18.8 μM
    Compound: Curcumin
    Antiproliferative activity against human PC3 cells up to 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells up to 72 hrs by MTT assay
    		[PMID: 28319780]
    PC-3 IC50
    25.43 μM
    Compound: 1
    Antiproliferative activity against androgen-insensitive human PC3 cells assessed as decrease in cell viability after 3 days by WST assay
    Antiproliferative activity against androgen-insensitive human PC3 cells assessed as decrease in cell viability after 3 days by WST assay
    		[PMID: 30121214]
    PC-3 IC50
    25.43 μM
    Compound: Curcumin
    Antiproliferative activity against human PC3 cells assessed as decrease in cell viability after 3 days by WST assay
    Antiproliferative activity against human PC3 cells assessed as decrease in cell viability after 3 days by WST assay
    		[PMID: 28601720]
    PC-3 IC50
    25.43 μM
    Compound: 1
    Antiproliferative activity against human PC3 cells after 3 days by WST-1 assay
    Antiproliferative activity against human PC3 cells after 3 days by WST-1 assay
    		[PMID: 28388523]
    PC-3 IC50
    25.43 μM
    Compound: 1a; Curcumin
    Antiproliferative activity against human PC3 cells assessed as inhibition of cell viability after 3 days by WST-1 assay
    Antiproliferative activity against human PC3 cells assessed as inhibition of cell viability after 3 days by WST-1 assay
    		[PMID: 26827161]
    PC-3 IC50
    25.43 μM
    Compound: Curcumin
    Antiproliferative activity against human PC3 cells after 3 days by WST or trypan blue assay
    Antiproliferative activity against human PC3 cells after 3 days by WST or trypan blue assay
    		[PMID: 27543391]
    PC-3 IC50
    39 μM
    Compound: Curcumin
    Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    		[PMID: 27496212]
    PWR-1E IC50
    8.14 μM
    Compound: 1
    Antiproliferative activity against human PWR-1E cells after 3 days by WST-1 assay
    Antiproliferative activity against human PWR-1E cells after 3 days by WST-1 assay
    		[PMID: 28388523]
    PWR-1E IC50
    8.85 μM
    Compound: Curcumin
    Antiproliferative activity against human PWR-1E cells expressing androgen receptor and PSA assessed as decrease in cell viability after 3 days by WST assay
    Antiproliferative activity against human PWR-1E cells expressing androgen receptor and PSA assessed as decrease in cell viability after 3 days by WST assay
    		[PMID: 28601720]
    QG-56 IC50
    100 μM
    Compound: Curcumin
    Cytotoxicity against human QG56 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human QG56 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 27318975]
    QG-56 IC50
    100 μM
    Compound: Curcumin
    Cytotoxicity against human QG56 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human QG56 cells assessed as cell viability after 48 hrs by MTT assay
    		[PMID: 26810315]
    QGY-7703 IC50
    21.44 μM
    Compound: Curcumin
    Cytotoxicity against human QGY7703 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human QGY7703 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		[PMID: 29909338]
    QGY-7703 IC50
    22.5 μM
    Compound: Curcumin
    Cytotoxicity against human QGY-7703 cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay
    Cytotoxicity against human QGY-7703 cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay
    		[PMID: 34450496]
    QGY-7703 IC50
    23.91 μM
    Compound: Curcumin
    Cytotoxicity against human QGY7703 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
    Cytotoxicity against human QGY7703 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
    		[PMID: 30771605]
    RAW264.7 IC50
    > 100 μM
    Compound: Curcumin
    Cytotoxicity against mouse RAW264.7 cells by MTT assay
    Cytotoxicity against mouse RAW264.7 cells by MTT assay
    		10.1039/C4MD00541D
    RAW264.7 IC50
    0.8 μM
    Compound: Curcumin
    Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells measured after 20 hrs by griess assay
    Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells measured after 20 hrs by griess assay
    		[PMID: 30108997]
    RAW264.7 IC50
    1.89 μM
    Compound: Curcumin
    Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated with compound for 2 hrs followed by LPS stimulation for 24 hrs by Griess reagent based assay
    Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated with compound for 2 hrs followed by LPS stimulation for 24 hrs by Griess reagent based assay
    		[PMID: 35576655]
    RAW264.7 IC50
    11.2 μM
    Compound: Curcumin
    Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha level preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by ELISA
    Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha level preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by ELISA
    		[PMID: 33422907]
    RAW264.7 IC50
    12.3 μM
    Compound: Curcumin
    Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess method
    Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess method
    		[PMID: 33422907]
    RAW264.7 IC50
    14.7 μM
    Compound: Curcumin
    Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS/IFN-gamma-stimulated nitric oxide production after 17 hrs by Griess assay
    Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS/IFN-gamma-stimulated nitric oxide production after 17 hrs by Griess assay
    		10.1039/C4MD00541D
    RAW264.7 IC50
    15.95 μM
    Compound: Curcumin
    Inhibition of LPS/IFN-gamma-induced PGE2 production in mouse RAW264.7 cells after 17 to 20 hrs by enzyme immunoassay
    Inhibition of LPS/IFN-gamma-induced PGE2 production in mouse RAW264.7 cells after 17 to 20 hrs by enzyme immunoassay
    		[PMID: 27040659]
    RAW264.7 IC50
    19.1 μM
    Compound: Curcumin
    Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
    Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
    		[PMID: 26841168]
    RAW264.7 IC50
    2.2 μM
    Compound: Curcumin
    Antiinflammatory activity in mouse RAW 264.7 cells assessed as inhibition of LPS-induced NO production measured after 24 hrs by Griess assay
    Antiinflammatory activity in mouse RAW 264.7 cells assessed as inhibition of LPS-induced NO production measured after 24 hrs by Griess assay
    		[PMID: 35029398]
    RAW264.7 IC50
    3 μM
    Compound: 1
    Inhibition of RANKL-induced osteoclastogenesis in murine RAW264.7 cells assessed as formation of TRAP positive multinucleated osteoclasts pretreated for 4 hrs followed by RANKL addition measured after 72 hrs
    Inhibition of RANKL-induced osteoclastogenesis in murine RAW264.7 cells assessed as formation of TRAP positive multinucleated osteoclasts pretreated for 4 hrs followed by RANKL addition measured after 72 hrs
    		[PMID: 30794412]
    RAW264.7 IC50
    3.5 μM
    Compound: Curcumin
    Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 24 hrs by Griess reagent based assay
    Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 24 hrs by Griess reagent based assay
    		[PMID: 34726063]
    SAOS-2 EC50
    28.1 μM
    Compound: Curcumin
    Cytotoxicity against human Saos2 cells expressing p53 mutant after 48 hrs by crystal violet-staining based spectrophotometric assay
    Cytotoxicity against human Saos2 cells expressing p53 mutant after 48 hrs by crystal violet-staining based spectrophotometric assay
    		[PMID: 26606246]
    SAOS-2 EC50
    48.6 μM
    Compound: Curcumin
    Cytotoxicity against human Saos2 cells expressing p53 mutant after 24 hrs by crystal violet-staining based spectrophotometric assay
    Cytotoxicity against human Saos2 cells expressing p53 mutant after 24 hrs by crystal violet-staining based spectrophotometric assay
    		[PMID: 26606246]
    Sf21 IC50
    25 μM
    Compound: Curcumin
    Inhibition of recombinant human full-length His6-tagged p300 expressed in baculovirus infected Sf21 insect cells using [3H]acetylCoA as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by liquid scintillation co
    Inhibition of recombinant human full-length His6-tagged p300 expressed in baculovirus infected Sf21 insect cells using [3H]acetylCoA as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by liquid scintillation co
    		[PMID: 31910017]
    SGC-7901 IC50
    > 20 μM
    Compound: 1; CUR
    Antiproliferative activity against human SGC7901 cells after 24 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells after 24 hrs by MTT assay
    		[PMID: 31129455]
    SGC-7901 IC50
    24.41 μM
    Compound: CUR
    Cytotoxicity against human SGC7901 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
    Cytotoxicity against human SGC7901 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
    		[PMID: 26318057]
    SGC-7901 IC50
    26.2 μM
    Compound: Curcumin
    Cytotoxicity against human SGC7901 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    		[PMID: 29288946]
    SH-SY5Y IC50
    16.1 μM
    Compound: 1
    Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs
    Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs
    		[PMID: 26705144]
    SH-SY5Y EC50
    5.29 μM
    Compound: Curcumin
    Neuroprotective activity against 6-OHDA induced cell death in human SH-SY5Y cells preincubated with 6-hyrdoxydopamine followed by compound addition and measured after 24 hrs by MTT assay
    Neuroprotective activity against 6-OHDA induced cell death in human SH-SY5Y cells preincubated with 6-hyrdoxydopamine followed by compound addition and measured after 24 hrs by MTT assay
    		[PMID: 35968659]
    SH-SY5Y EC50
    6.2 μM
    Compound: Curcumin
    Neuroprotective activity in human SH-SY5Y cells assessed as reduction in 6-OHDA-induced cell death measured after 24 hrs by MTT assay
    Neuroprotective activity in human SH-SY5Y cells assessed as reduction in 6-OHDA-induced cell death measured after 24 hrs by MTT assay
    		[PMID: 27420919]
    SK-BR-3 IC50
    42.83 μM
    Compound: Curcumin
    Antiproliferative activity against HER2 positive human SKBR3 cells after 24 hrs by MTT assay
    Antiproliferative activity against HER2 positive human SKBR3 cells after 24 hrs by MTT assay
    		[PMID: 28319780]
    SK-MEL-2 IC50
    36 μM
    Compound: Curc
    Cytotoxicity against human SK-MEL-2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human SK-MEL-2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 28654265]
    SK-OV-3 IC50
    43.63 μM
    Compound: 18, Curcumin, Diferuloylmethane
    Cytotoxicity against human SKOV3 cells after 24 hrs by MTT assay
    Cytotoxicity against human SKOV3 cells after 24 hrs by MTT assay
    		[PMID: 26174555]
    SK-OV-3 IC50
    49.85 μM
    Compound: Curcumin
    Cytotoxicity against human SKOV3 cells by MTT assay
    Cytotoxicity against human SKOV3 cells by MTT assay
    		[PMID: 26873414]
    SK-OV-3 IC50
    6.7 μM
    Compound: 1; CUR
    Cytotoxicity against human SKOV3 Cells after 48 hrs by Cell Titer Blue assay
    Cytotoxicity against human SKOV3 Cells after 48 hrs by Cell Titer Blue assay
    		[PMID: 31129455]
    SMMC-7721 IC50
    12.57 μM
    Compound: 1; CUR
    Anticancer activity against human SMMC7721 cells after 72 hrs by MTT assay
    Anticancer activity against human SMMC7721 cells after 72 hrs by MTT assay
    		[PMID: 31129455]
    SMMC-7721 IC50
    16.68 μM
    Compound: Curcumin
    Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
    Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
    		[PMID: 30771605]
    SMMC-7721 IC50
    18.8 μM
    Compound: Curcumin
    Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay
    Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay
    		[PMID: 34450496]
    SMMC-7721 IC50
    19.47 μM
    Compound: Curcumin
    Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		[PMID: 29909338]
    SW480 IC50
    10 μM
    Compound: Curcumin
    Inhibition of chymotrypsin-like activity of human 26S proteasome in human SW480 cells assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as substrate preincubated for 24 hrs followed by addition of substrate and measured after 2 hrs by fluorometric
    Inhibition of chymotrypsin-like activity of human 26S proteasome in human SW480 cells assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as substrate preincubated for 24 hrs followed by addition of substrate and measured after 2 hrs by fluorometric
    		[PMID: 30776692]
    SW480 IC50
    15 μM
    Compound: 1; CUR
    Cytotoxicity against human SW480 Cells after 24 to 48 hrs by MTT assay
    Cytotoxicity against human SW480 Cells after 24 to 48 hrs by MTT assay
    		[PMID: 31129455]
    SW480 IC50
    17.94 μM
    Compound: CU
    Cytotoxicity against human SW480 cells after 4 hrs by MTT assay
    Cytotoxicity against human SW480 cells after 4 hrs by MTT assay
    		[PMID: 31336310]
    SW-620 IC50
    12.52 μM
    Compound: CUR
    Cytotoxicity against human SW620 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
    Cytotoxicity against human SW620 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
    		[PMID: 26318057]
    SW-620 IC50
    14 μM
    Compound: Curcumin
    Cytotoxicity against human SW620 cells after 72 hrs by MTT assay
    Cytotoxicity against human SW620 cells after 72 hrs by MTT assay
    		[PMID: 30138803]
    T47D IC50
    19 μM
    Compound: Curc
    Cytotoxicity against human T47D cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human T47D cells assessed as decrease in cell viability after 48 hrs by MTT assay
    		[PMID: 28654265]
    T47D IC50
    30 μM
    Compound: Curcumin
    Cytotoxicity against human T47D cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human T47D cells assessed as reduction in cell viability after 24 hrs by MTT assay
    		[PMID: 27517806]
    T47D IC50
    47.91 μM
    Compound: Curcumin
    Antiproliferative activity against ER/PR positive human T47D cells after 24 hrs by MTT assay
    Antiproliferative activity against ER/PR positive human T47D cells after 24 hrs by MTT assay
    		[PMID: 28319780]
    T98G IC50
    10 μM
    Compound: curcumin
    Antiproliferative activity against human T98G cells after 24 hrs by EZ-Tox assay
    Antiproliferative activity against human T98G cells after 24 hrs by EZ-Tox assay
    		[PMID: 26631318]
    T98G IC50
    25 μM
    Compound: curcumin
    Antiproliferative activity against human T98G cells assessed as cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human T98G cells assessed as cell viability after 72 hrs by MTT assay
    		[PMID: 26631318]
    THP-1 IC50
    22.54 μM
    Compound: Curcumin
    Cytotoxicity against human THP1 cells assessed as reduction in cell viability after 24 hrs by MTT assay