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  1. Anti-infection
  2. Bacterial Antibiotic
  3. Sulfathiazole

Sulfathiazole  (Synonyms: 磺胺噻唑)

目錄號: HY-B0507 純度: 99.71%
COA 產(chǎn)品使用指南 技術(shù)支持

Sulfathiazole 是一種有機硫化合物,是短效的磺胺類抗生素。

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Sulfathiazole Chemical Structure

Sulfathiazole Chemical Structure

CAS No. : 72-14-0

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10 mM * 1 mL in DMSO ¥220
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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Sulfathiazole, an organosulfur compound, is used as a short-acting sulfonamide antibiotic[1][2][3].

IC50 & Target

Antibacterial

細(xì)胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 IC50
4161 μM
Compound: 3a
Cytotoxicity against human HepG2 cells after 24 hrs by MTS assay
Cytotoxicity against human HepG2 cells after 24 hrs by MTS assay
[PMID: 22365879]
Sf9 IC50
430 μM
Compound: 19
Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity assay
Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-S-adenosylmethionine by scintillation proximity assay
[PMID: 26824386]
體外研究
(In Vitro)

Sulfathiazole (20 μg/L) starts to be degraded between day 31 and day 38 in one of the two batch reactors containing different wastewater matrices. Sulfathiazole is degraded at a substantially faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3)[1]. Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level[2]]. Sulfathiazole sorption to inorganic sorbents exhibits pronounced pH dependence consistent with sorbate speciation and sorbent charge properties. Sulfathiazole cations are most important for sorption to clay minerals, followed by neutral species[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

255.32

Formula

C9H9N3O2S2

CAS 號
性狀

固體

顏色

White to off-white

中文名稱

磺胺噻唑;磺胺塞唑

運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性數(shù)據(jù)
細(xì)胞實驗: 

DMSO 中的溶解度 : 250 mg/mL (979.15 mM; 超聲助溶; 吸濕的 DMSO 對產(chǎn)品的溶解度有顯著影響,請使用新開封的 DMSO)

配制儲備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 3.9166 mL 19.5830 mL 39.1659 mL
5 mM 0.7833 mL 3.9166 mL 7.8332 mL
查看完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液;一旦配成溶液,請分裝保存,避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C儲存時,請在6個月內(nèi)使用,-20°C儲存時,請在1個月內(nèi)使用。

  • 摩爾計算器

  • 稀釋計算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動物溶解方案計算器
請輸入動物實驗的基本信息:

給藥劑量

mg/kg

動物的平均體重

g

每只動物的給藥體積

μL

動物數(shù)量

由于實驗過程有損耗,建議您多配一只動物的量
計算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料
參考文獻

Sulfathiazole 相關(guān)分類

完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液;一旦配成溶液,請分裝保存,避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C儲存時,請在6個月內(nèi)使用,-20°C儲存時,請在1個月內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9166 mL 19.5830 mL 39.1659 mL 97.9148 mL
5 mM 0.7833 mL 3.9166 mL 7.8332 mL 19.5830 mL
10 mM 0.3917 mL 1.9583 mL 3.9166 mL 9.7915 mL
15 mM 0.2611 mL 1.3055 mL 2.6111 mL 6.5277 mL
20 mM 0.1958 mL 0.9791 mL 1.9583 mL 4.8957 mL
25 mM 0.1567 mL 0.7833 mL 1.5666 mL 3.9166 mL
30 mM 0.1306 mL 0.6528 mL 1.3055 mL 3.2638 mL
40 mM 0.0979 mL 0.4896 mL 0.9791 mL 2.4479 mL
50 mM 0.0783 mL 0.3917 mL 0.7833 mL 1.9583 mL
60 mM 0.0653 mL 0.3264 mL 0.6528 mL 1.6319 mL
80 mM 0.0490 mL 0.2448 mL 0.4896 mL 1.2239 mL
100 mM 0.0392 mL 0.1958 mL 0.3917 mL 0.9791 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱:
Sulfathiazole
目錄號:
HY-B0507
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