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  2. Anti-infection
  3. Reverse Transcriptase
  4. Tenofovir diphosphate

Tenofovir diphosphate  (Synonyms: TFV-DP)

目錄號: HY-136548
產(chǎn)品使用指南 技術支持

Tenofovir diphosphate (TFV-DP) 是一種 ATP 競爭性的 DNA 聚合酶 (DNA polymerases) 抑制劑，且是 1 型 HIV (HIV-1) 逆轉(zhuǎn)錄酶 (RT) 的底物。

該游離形式化合物不穩(wěn)定，推薦具有相同生物學活性的穩(wěn)定鹽形式 Tenofovir diphosphate disodium。

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Tenofovir diphosphate Chemical Structure

Tenofovir diphosphate Chemical Structure

CAS No. : 166403-66-3

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Tenofovir diphosphate 的其他形式現(xiàn)貨產(chǎn)品:

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Other Forms of Tenofovir diphosphate:

MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Tenofovir diphosphate (TFV-DP) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].

IC50 & Target

DNA polymerases; HIV-1 reverse transcriptase[1]
體外研究
(In Vitro)

Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and ?, with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

447.17

Formula

C9H16N5O10P3
CAS 號
中文名稱

替諾福韋二磷酸酯
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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產(chǎn)品名稱：
Tenofovir diphosphate
目錄號：
HY-136548
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