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  2. Epigenetics Autophagy PI3K/Akt/mTOR
  3. Autophagy AMPK
  4. Resolvin D3

Resolvin D3 (RvD3) 是二十二碳六烯酸 (DHA) 衍生的介體。Resolvin D3 在關(guān)節(jié)炎中失調(diào)，可減輕關(guān)節(jié)炎癥。

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Resolvin D3 Chemical Structure

Resolvin D3 Chemical Structure

CAS No. : 916888-47-6

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規(guī)格 價(jià)格 是否有貨
25 μg (265.6 μM * 250 μL in Ethanol) ￥8800
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Customer Review

Other Forms of Resolvin D3:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2].

體外研究
(In Vitro)

RvD3 (RvD3; 10 nM) significantly inhibits tumor necrosis factor-α–induced NF-κB activation in A549 epithelial cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
體內(nèi)研究
(In Vivo)

Resolvin D3 (RvD3; 100 ng/100 μl; IP; daily for 6 days) alleviates arthritis progression, reduces edema and limits leukocyte numbers in murine K/BxN-serum induced arthritis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice[1]
Dosage: 100 ng/100 μl
Administration: IP; daily for 6 days
Result: Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis.
分子量

376.49

Formula

C22H32O5
CAS 號(hào)
性狀

液體

顏色

Colorless to light yellow

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

Solution, -20°C, 2 years
純度 & 產(chǎn)品資料

純度: ≥95.0%

參考文獻(xiàn)

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  • Do most proteins show cross-species activity?

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產(chǎn)品名稱：
Resolvin D3
目錄號(hào)：
HY-136540
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