5 | 1189966-73-1 | BW 759-d5 | 2'-Nor-2'-deoxyguanosine-d5 | 更昔洛韋 d5 | Isotope-Labeled Compounds | CMV | HSV | Antibiotic | Nucleoside Antimetabolite/Analog | Cytomegalovirus | Herpes simplex virus | Inhibitor | inhibitor | inhibit"/>

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  2. Others Anti-infection Cell Cycle/DNA Damage
  3. Isotope-Labeled Compounds CMV HSV Antibiotic Nucleoside Antimetabolite/Analog
  4. Ganciclovir-d5

Ganciclovir-d5  (Synonyms: BW 759-d5; 2'-Nor-2'-deoxyguanosine-d5)

目錄號: HY-13637S 純度: 98.32%
COA 產(chǎn)品使用指南 技術(shù)支持

Ganciclovir-d5 是 Ganciclovir 的氘代物。Ganciclovir (BW 759) 是一種核苷類似物和口服抗病毒活性分子，對 CMV 具有抗病毒活性。Ganciclovir 在體外對皰疹病毒 (herpes group) 和其他一些 DNA 病毒也具有抗病毒活性。Ganciclovir 抑制人類皰疹病毒 (HSV 1 型和 2 型，CMV) 和腺病毒血清型1、2、4、6、8、10、19、22 和 28 的體外復制。Ganciclovir 對貓 1 型皰疹病毒 (FHV-1) 的IC50為 5.2 μM。

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Ganciclovir-d<sub>5</sub> Chemical Structure

Ganciclovir-d5 Chemical Structure

CAS No. : 1189966-73-1

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥6730
In-stock
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Other Forms of Ganciclovir-d5:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Ganciclovir-d5 is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1)[1][2][3].

體外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

260.26

Formula

C9H8D5N5O4
CAS 號
非標記 CAS
性狀

固體

顏色

White to off-white

中文名稱

更昔洛韋 d5
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: 98.32%

參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Ganciclovir-d5
目錄號：
HY-13637S
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