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  2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Sepimostat dimethanesulfonate

Sepimostat dimethanesulfonate  (Synonyms: FUT-187)

目錄號: HY-136299A
產(chǎn)品使用指南

Sepimostat dimethanesulfonate (FUT-187) 通過拮抗 NR2B N-methyl-D-aspartate 受體發(fā)揮神經(jīng)保護(hù)作用， 作用位點(diǎn)在NR2B 亞基的 Ifenprodil 結(jié)合位點(diǎn)。Sepimostat dimethanesulfonate 抑制 Ifenprodil 結(jié)合的 Ki 值為 27.7?μM。

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Sepimostat dimethanesulfonate Chemical Structure

Sepimostat dimethanesulfonate Chemical Structure

CAS No. : 103926-82-5

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Sepimostat dimethanesulfonate 的其他形式現(xiàn)貨產(chǎn)品:

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Other Forms of Sepimostat dimethanesulfonate:

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查看 iGluR 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Sepimostat dimethanesulfonate (FUT-187) exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat dimethanesulfonate inhibits the Ifenprodil binding with a Ki value of 27.7?μM[1].

體內(nèi)研究
(In Vivo)

Sepimostat (1 to 100 nmol/eye, intravitreal injection) exhibits significant neuroprotective effect[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague Dawley rats weighing 150-300?g[1].
Dosage: Intravitreal injection.
Administration: 1 to 100 nmol/eye.
Result: Exhibited neuroprotective effects significantly.
分子量

565.62

Formula

C23H27N5O8S2
CAS 號
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

Sepimostat dimethanesulfonate 相關(guān)分類

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Sepimostat dimethanesulfonate
目錄號：
HY-136299A
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