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  1. Metabolic Enzyme/Protease Apoptosis
  2. NAMPT Apoptosis
  3. STF-118804

STF-118804是煙酰胺磷酸核糖基轉(zhuǎn)移酶NAMPT高選擇性抑制劑,對多個(gè) B 細(xì)胞系活力的抑制作用的IC50 小于10nM。

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STF-118804 Chemical Structure

STF-118804 Chemical Structure

CAS No. : 894187-61-2

1.  客戶無需承擔(dān)相應(yīng)的運(yùn)輸費(fèi)用。

2.  同一機(jī)構(gòu)(單位)同一產(chǎn)品試用裝僅限申領(lǐng)一次,同一機(jī)構(gòu)(單位)一年內(nèi)

     可免費(fèi)申領(lǐng)三個(gè)不同產(chǎn)品的試用裝。

3.  試用裝只面向終端客戶。

規(guī)格 價(jià)格 是否有貨 數(shù)量
10 mM * 1 mL in DMSO ¥660
In-stock
5 mg ¥600
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10 mg ¥920
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25 mg ¥1900
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50 mg ¥3100
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100 mg ¥4600
In-stock
200 mg   詢價(jià)  
500 mg   詢價(jià)  

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Customer Review

MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻(xiàn)

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.

細(xì)胞效力
(Cellular Effect)
Cell Line Type Value Description References
B-ALL EC50
0.061 μM
Compound: 1
Antiproliferative activity against mouse B-ALL BCR-ABL double knockout cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against mouse B-ALL BCR-ABL double knockout cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
B-ALL EC50
0.072 μM
Compound: 1
Antiproliferative activity against mouse B-ALL cells expressing wild type BCR-ABL assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against mouse B-ALL cells expressing wild type BCR-ABL assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
BJ EC50
2.4938 μM
Compound: 1
Antiproliferative activity against human BJ assessed as cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human BJ assessed as cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
K562 EC50
4.6 μM
Compound: 1
Antiproliferative activity against human K562 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human K562 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
KOPN-8 EC50
1.23 μM
Compound: 1
Antiproliferative activity against human KOPN8 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human KOPN8 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
MV4-11 EC50
3.8 μM
Compound: 1
Antiproliferative activity against human MV411 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human MV411 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
NALM-6 EC50
0.026 μM
Compound: 1
Antiproliferative activity against human NALM6 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human NALM6 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
SUP-B15 EC50
1.1 μM
Compound: 1
Antiproliferative activity against human SUP-B15 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human SUP-B15 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
UoC-B1 EC50
> 54.98 μM
Compound: 1
Antiproliferative activity against human UOCB1 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human UOCB1 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
分子量

461.53

Formula

C25H23N3O4S

CAS 號
性狀

固體

顏色

White to light yellow

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
溶解性數(shù)據(jù)
細(xì)胞實(shí)驗(yàn): 

DMSO 中的溶解度 : 25 mg/mL (54.17 mM; 超聲助溶; 吸濕的 DMSO 對產(chǎn)品的溶解度有顯著影響,請使用新開封的 DMSO)

配制儲(chǔ)備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 2.1667 mL 10.8335 mL 21.6671 mL
5 mM 0.4333 mL 2.1667 mL 4.3334 mL
查看完整儲(chǔ)備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液;一旦配成溶液,請分裝保存,避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限:-80°C, 2 years; -20°C, 1 year。-80°C儲(chǔ)存時(shí),請?jiān)?年內(nèi)使用, -20°C儲(chǔ)存時(shí),請?jiān)?年內(nèi)使用。

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動(dòng)物溶解方案計(jì)算器
請輸入動(dòng)物實(shí)驗(yàn)的基本信息:

給藥劑量

mg/kg

動(dòng)物的平均體重

g

每只動(dòng)物的給藥體積

μL

動(dòng)物數(shù)量

由于實(shí)驗(yàn)過程有損耗,建議您多配一只動(dòng)物的量
計(jì)算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料

純度: 99.72%

參考文獻(xiàn)

STF-118804 相關(guān)分類

完整儲(chǔ)備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液;一旦配成溶液,請分裝保存,避免反復(fù)凍融造成的產(chǎn)品失效
儲(chǔ)備液的保存方式和期限:-80°C, 2 years; -20°C, 1 year。-80°C儲(chǔ)存時(shí),請?jiān)?年內(nèi)使用, -20°C儲(chǔ)存時(shí),請?jiān)?年內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1667 mL 10.8335 mL 21.6671 mL 54.1677 mL
5 mM 0.4333 mL 2.1667 mL 4.3334 mL 10.8335 mL
10 mM 0.2167 mL 1.0834 mL 2.1667 mL 5.4168 mL
15 mM 0.1444 mL 0.7222 mL 1.4445 mL 3.6112 mL
20 mM 0.1083 mL 0.5417 mL 1.0834 mL 2.7084 mL
25 mM 0.0867 mL 0.4333 mL 0.8667 mL 2.1667 mL
30 mM 0.0722 mL 0.3611 mL 0.7222 mL 1.8056 mL
40 mM 0.0542 mL 0.2708 mL 0.5417 mL 1.3542 mL
50 mM 0.0433 mL 0.2167 mL 0.4333 mL 1.0834 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

產(chǎn)品名稱:
STF-118804
目錄號:
HY-12808
需求量: