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  2. Metabolic Enzyme/Protease
  3. Drug Metabolite Endogenous Metabolite
  4. Acetaminophen glucuronide

Acetaminophen glucuronide  (Synonyms: APAP-glu)

目錄號: HY-113083 純度: ≥99.0%
COA 產(chǎn)品使用指南

Acetaminophen glucuronide (APAP-glu) 是 Acetaminophen (HY-66005) 的無活性葡萄糖醛酸代謝物。Acetaminophen 是一種選擇性環(huán)氧合酶 2 (COX-2) 抑制劑，也是有效的肝 N-乙酰轉(zhuǎn)移酶 2 (NAT2) 抑制劑。

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Acetaminophen glucuronide Chemical Structure

Acetaminophen glucuronide Chemical Structure

CAS No. : 16110-10-4

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥1650
In-stock
5 mg ￥3600
In-stock
10 mg   詢價  
50 mg   詢價  

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Customer Review

Other Forms of Acetaminophen glucuronide:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005)[1][2]. Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[3][4].

IC50 & Target

Human Endogenous Metabolite

 

體外研究
(In Vitro)

Acetaminophen is metabolized in the liver mainly by glucuronidation and sulfation, thus generating the nontoxic metabolites, Acetaminophen glucuronide (APAP-glu). Acetaminophen glucuronide is a substrate for both canalicular Mrp2 and basolateral Mrp3 in rodents[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

327.29

Formula

C14H17NO8
CAS 號
性狀

固體

顏色

White to off-white

中文名稱

對乙酰氨基酚葡萄糖醛酸
結(jié)構(gòu)分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: ≥99.0%

參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Acetaminophen glucuronide
目錄號：
HY-113083
需求量：