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  2. Antibody-drug Conjugate/ADC Related
  3. ADC Antibody
  4. Gemtuzumab

Gemtuzumab  (Synonyms: 吉妥珠單抗)

目錄號: HY-P99971 純度: 99.54%
COA 技術(shù)支持

Gemtuzumab 是一種靶向 CD33 抗原的 IgG4-κ 單克隆抗體，該抗原存在于急性髓系白血病 (AML) 的白血病成髓細(xì)胞上。Gemtuzumab 可用于合成一種抗體偶聯(lián)藥物 (ADC)，Gemtuzumab ozogamicin (HY-109539)。Gemtuzumab ozogamicin 由加利車霉素 (一種細(xì)胞毒性抗生素) 的細(xì)胞毒性衍生物和單克隆抗體組成。 Gemtuzumab ozogamicin 可用于急性髓性白血病的研究。

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥3400
In-stock
5 mg ￥8400
In-stock
10 mg   詢價  
50 mg   詢價  

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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC), Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia[1][2].

同型

Human IgG4 kappa
推薦同型對照抗體
種屬

Humanized
Clinical Trial
性狀

液體

顏色

Colorless to light yellow

中文名稱

吉妥珠單抗
運輸條件

Shipping with dry ice.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
Biological Activity
  • Immobilized Siglec-3/CD33 Protein, Human can bind Gemtuzumab. The EC50 for this effect is 4.328 ng/mL.
純度 & 產(chǎn)品資料

純度: 99.54%

參考文獻(xiàn)

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Gemtuzumab
目錄號：
HY-P99971
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