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  2. Metabolic Enzyme/Protease PROTAC GPCR/G Protein
  3. PROTAC Linkers Endogenous Metabolite Leukotriene Receptor
  4. Leukotriene B4

Leukotriene B4  (Synonyms: LTB4; 5(S),12(R)-DiHETE)

目錄號(hào): HY-107608 純度: ≥98.0%
COA 產(chǎn)品使用指南

Leukotriene B4 (LTB4) 是白細(xì)胞最有效的化學(xué)誘導(dǎo)劑和激活劑之一，參與多種炎癥性疾病。Leukotriene B4 是一種 PROTAC linker，屬于 alkyl chain 類?？捎糜诤铣?PROTAC 分子。

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Leukotriene B4 Chemical Structure

Leukotriene B4 Chemical Structure

CAS No. : 71160-24-2

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規(guī)格 價(jià)格 是否有貨 數(shù)量
25 μg (297.2 μM * 250 μL in Ethanol) ￥5850
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Other Forms of Leukotriene B4:

MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻(xiàn)

查看 PROTAC Linkers 亞型特異性產(chǎn)品:

查看 Leukotriene Receptor 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2][3].

IC50 & Target

Alkyl-Chain

 

Human Endogenous Metabolite

 

體外研究
(In Vitro)

Leukotriene B4 誘導(dǎo)中性粒細(xì)胞、單核細(xì)胞和嗜酸性粒細(xì)胞的募集和激活。它還會(huì)刺激多種促炎細(xì)胞因子和介質(zhì)的產(chǎn)生，表明其具有增強(qiáng)和延長(zhǎng)組織炎癥的能力[2]。
Leukotriene B4 是一種在骨髓細(xì)胞中合成的促炎介質(zhì)，來(lái)自花生四烯酸[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

336.47

Formula

C20H32O4
CAS 號(hào)
性狀

液體

顏色

Colorless to light yellow

結(jié)構(gòu)分類
初始來(lái)源
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

Solution, -20°C, 2 years
純度 & 產(chǎn)品資料

純度: ≥98.0%

參考文獻(xiàn)

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Leukotriene B4
目錄號(hào)：
HY-107608
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