Identification | Back Directory | [Name]
D-gamma-Tocotrienol | [CAS]
14101-61-2 | [Synonyms]
D-G-TOCOTRIENOL Gama-Tocotrienol D-GAMMA-TOCOTRIENOL (R)-gamma-Tocotrienol 7,8-Dimethyltocotrienol 6-Chromanol, 2,7,8-trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)- (7ci,8ci) (R-(E,E))-3,4-Dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol (R)-3,4-Dihydro-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-, [R-(E,E)]- (2R)-2β,7,8-Trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-3,4-dihydro-2H-1-benzopyran-6-ol 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-, (2R)- 2H-1-Benzopyran-6-ol,3,4-dihydro-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-,(2R)- 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,7,8-trimethyl-2-[(3E,7E)-4,8,12-tr imethyl-3,7,11-tridecatrienyl]-, (2R)- (9CI) (R-(all-E))-3,4-Dihydro-2,7,8-trimethyl-2-(4,8,12,16,20,24,28,32-octamethyl-3,7,11,15,19,23,27,31-tritriacontaoctaenyl)-2H-1-benzopyran-6-ol | [Molecular Formula]
C28H42O2 | [MDL Number]
MFCD05864856 | [MOL File]
14101-61-2.mol | [Molecular Weight]
410.63 |
Chemical Properties | Back Directory | [Boiling point ]
530.8±49.0 °C(Predicted) | [density ]
0.964±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
neat | [pka]
11.05±0.40(Predicted) | [color ]
Very Dark Yellow Thick | [Stability:]
Light Sensitive | [LogP]
10.300 (est) |
Hazard Information | Back Directory | [Description]
γ-Tocotrienol is a form of vitamin E that has been found in rice bran and has diverse biological activities.1,2 It reduces cell death induced by hydrogen peroxide, paraquat, S-nitrocysteine, SIN-1 (Item No. 82220), or L-buthionine-(S,R)-sulfoximine (BSO; Item No. 14484) in rat striatal cultures when used at concentrations ranging from 0.1 to 10 μM.2 γ-Tocotrienol (20 μM) induces apoptosis in malignant sympathoadrenal (+SA) mouse mammary epithelial cells.3 In vivo, γ-tocotrienol (15, 30, and 150 mg/kg) reduces blood pressure and plasma lipid peroxide levels in spontaneously hypertensive rats.4 [Matreya, LLC. Catalog No. 2111] | [Chemical Properties]
g:d:aTocotrienol 1.6:0.4:1 | [Uses]
γ-Tocotrienol exhibits antioxidant properties and belongs to the vitamin E family. It is naturally found in wheat germ oil and bran. In addition, α-tocopherol and γ-tocotrienol derivatives are potential lead compounds for developing?anticancer and?antiproliferative agents against?MCF-7 and MDA-MB-231 breast cancer cells and the A549 lung cancer cells. | [Definition]
ChEBI: A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 7 and 8 and a farnesyl chain at position 2. |
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