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SKF-82958 (hydrobromide)

  Cat. No.:  DC9420  
Chemical Structure
74115-01-8
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More than 5000 active chemicals with high quality for research!
Field of application
SKF 82958 hydrobromide is a D1/D5 receptor full agonist.
Cas No.: 74115-01-8
Synonyms: (±)-SKF 82958 hydrobromide;Chloro-APB hydrobromide
SMILES: OC1=C(O)C=C2C(C3=CC=CC=C3)CN(CC=C)CCC2=C1Cl.[H]Br
Formula: C19H21BrClNO2
M.Wt: 410.7325
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: SKF 82958 hydrobromide is a D1/D5 receptor full agonist. in vitro: Neuropeptide and immediate early gene expression in striatonigral neurons of the normosensitive striatum is induced by mixed D1 receptor SKF-82958, which induces behavioral activity and preprodynorphin (PPD) and substance P (SP) gene expression in medium spiny neurons in the dorsal, and especially, in the ventral striatum. in vivo:Quantitative in situ hybridization was used to examine the contribution of muscarinic receptors to the transynaptic regulation of striatal gene expression induced by D1receptor activation. The acute injection of the full D1 agonist, SKF-82958, would induce PPD, SP and PPE mRNA expression in the intact rat striatum.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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