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AN3365(Epetraborole)

  Cat. No.:  DC9827   Featured
Chemical Structure
1234563-16-6
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More than 5000 active chemicals with high quality for research!
Field of application
AN3365 is a first-in-class antibiotic that demonstrates potent activity across a wide spectrum of Gram-negative bacteria, including those resistant to many other antibiotics.
Cas No.: 1234563-16-6
Chemical Name: Epetraborole HCl
Synonyms: (S)-3-(aminomethyl)-7-(3-hydroxypropoxy)benzo[c][1,2]oxaborol-1(3h)-ol;AN3365;GSK2251052 hydrochloride;GSK-2251052 hydrochloride;Epetraborole (hydrochloride);Epetraborole hydrochloride;Epetraborole HCl;MM0NZY12FA;(S)-3-(Aminomethyl)-7-(3-hydroxypropoxy)-1-hydroxy-1,3-dihydro-2,1-benzoxaborole hydrochloride;AN3365(Epetraborole);Epetraborole HCl, AN3365 HCl;1-Propanol, 3-(((3S)-3-(aminomethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl)oxy)-, hy
SMILES: Cl[H].O1B(C2C(=C([H])C([H])=C([H])C=2[C@@]1([H])C([H])([H])N([H])[H])OC([H])([H])C([H])([H])C([H])([H])O[H])O[H]
Formula: C11H17BClNO4
M.Wt: 273.52
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Epetraborole hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding "to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase". It is intended for the treatment of infections caused by Gram-negative bacteria. Epetraborole hydrochloride is a bacteriostatic compound that can against a wide range of anaerobic and Gram-negative bacteria, including multidrug-resistant pathogens, such as extended-spectrum-β-lactamase-, metallo-β-lactamase-, and carbapenemase-producing organism.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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