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  1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Acetic acid

Acetic acid 是一種短鏈脂肪酸 (SCFAs),其含量水平與中密度脂蛋白 (IDL-c) 的水平呈正相關(guān)。而 Propionic acid 與高密度脂蛋白 (HDL-P) 的水平呈負(fù)相關(guān)。Acetic acid 是大多數(shù)厭氧菌碳水化合物發(fā)酵代謝物,與肝臟中的“從頭”脂肪生成和膽固醇生成刺激有關(guān)。Acetic acid 與 Propionic acid 的比例是宿主脂質(zhì)譜狀態(tài)的新型生物標(biāo)志物。

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Acetic acid Chemical Structure

Acetic acid Chemical Structure

CAS No. : 64-19-7

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MCE 顧客使用本產(chǎn)品發(fā)表的 2 篇科研文獻(xiàn)

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Acetic acid is a type of short-chain fatty acids (SCFAs) whose content levels are positively correlated with intermediate-density lipoprotein (IDL-c) levels. Propionic acid is negatively correlated with high-density lipoprotein (HDL-P) levels. Acetic acid is a carbohydrate fermentation metabolite of most anaerobic bacteria and is associated with stimulation of "de novo" lipogenesis and cholesterol production in the liver. The ratio of acetic acid to propionic acid is a novel biomarker of host lipid profile status[1].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

細(xì)胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 EC50
12 μM
Compound: Acetate
Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method
Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method
[PMID: 28745893]
HEK293 EC50
250 μM
Compound: Acetate
Agonist activity at human GPCR43 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method
Agonist activity at human GPCR43 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method
[PMID: 28745893]
分子量

60.05

Formula

C2H4O2

CAS 號(hào)
性狀

液體(密度:1.049 g/cm3

顏色

Colorless to light yellow

中文名稱(chēng)

乙酸

初始來(lái)源
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: ≥99.0%

參考文獻(xiàn)
  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
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產(chǎn)品名稱(chēng):
Acetic acid
目錄號(hào):
HY-Y0319
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