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  2. Immunology/Inflammation
  3. Interleukin Related
  4. Sarilumab

Sarilumab  (Synonyms: 沙利魯單抗; Anti-Human IL6Rα, Human Antibody)

目錄號: HY-P9916 純度: 99.36%
COA 技術(shù)支持

Sarilumab (Anti-Human IL6Rα, Human Antibody) 是人免疫球蛋白 G1 單克隆抗體。Sarilumab 是白細(xì)胞介素-6 IL-6 受體的拮抗劑。 Sarilumab 與 IL-6 受體具有高親和力，并抑制 IL-6 的順式和反式信號傳導(dǎo)，減少炎癥。Sarilumab 可用于類風(fēng)濕關(guān)節(jié)炎的研究。

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥1900
In-stock
5 mg ￥5700
In-stock
10 mg ￥8835
In-stock
50 mg   詢價  
100 mg   詢價  

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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis[1][2].

同型

Human IgG1(E356D/M358L) kappa
推薦同型對照抗體
種屬

Human
IC50 & Target[1]

IL-6

 

Clinical Trial
性狀

液體

顏色

Colorless to light yellow

中文名稱

沙利魯單抗；薩瑞魯單抗
運(yùn)輸條件

Shipping with dry ice.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized IL-6R alpha Protein, Human can bind Sarilumab. The EC50 for this effect is 34.98 ng/mL.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Sarilumab
目錄號：
HY-P9916
需求量：