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  1. Immunology/Inflammation
  2. CD20 CD3
  3. Mosunetuzumab

Mosunetuzumab  (Synonyms: 莫妥珠單抗; BTCT-4465A)

目錄號: HY-P99033 純度: 99.05%
COA 技術(shù)支持

Mosunetuzumab (BTCT-4465A) 是一種全長、完全人源化免疫球蛋白 G1 (IgG1) T 細胞依賴性雙特異性 (TDB) 抗體,靶向 CD20 (B 細胞) 和 CD3 (T 細胞)。Mosunetuzumab 重定向 T 細胞以接合和消除惡性 B 細胞,可用于研究復(fù)發(fā)或難治性 (R/R) B 細胞非霍奇金淋巴瘤 (B-NHL)。

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CAS No. : 1905409-39-3

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ¥3400
In-stock
5 mg ¥8000
In-stock
10 mg ¥10716
In-stock
25 mg ¥15840
In-stock
50 mg ¥21480
In-stock
100 mg ¥28680
In-stock
200 mg   詢價  
500 mg   詢價  

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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs)[1][2].

同型

Human IgG1 kappa

推薦同型對照抗體
種屬

Bispecific; Humanized

體外研究
(In Vitro)

Mosunetuzumab 有兩個臂,一只臂特異性結(jié)合 T 細胞上的 CD3,另一臂特異性結(jié)合正常和腫瘤性 B 細胞上的 CD20,雙臂同時結(jié)合各自的靶標可促進 T 細胞介導(dǎo)的 CD20+ B 細胞殺傷[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS 號
性狀

液體

顏色

Colorless to light yellow

中文名稱

莫妥珠單抗

運輸條件

Shipping with dry ice.

儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG1 kappa
純度 & 產(chǎn)品資料

純度: 99.05%

參考文獻
  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

產(chǎn)品名稱:
Mosunetuzumab
目錄號:
HY-P99033
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