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  2. MAPK/ERK Pathway
  3. Raf
  4. R18

R18 是 14-3-3 的肽拮抗劑，其 KD 值為 70-90 nM。R18 可有效阻斷 14-3-3 與其配體 Raf-1激酶的結(jié)合，可有效地消除 14-3-3 對磷酸酶誘導(dǎo)的 Raf-1 失活的保護(hù)作用。

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Custom Peptide Synthesis

R18 Chemical Structure

R18 Chemical Structure

CAS No. : 211364-78-2

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥4527
1 - 2 周
5 mg   詢價  
10 mg   詢價  

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Customer Review

Other Forms of R18:

查看 Raf 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

R18 is a peptide antagonists of 14-3-3, with a KD of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1[1].

分子量

2309.69

Formula

C101H157N27O29S3
CAS 號
Sequence

Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro
Sequence Shortening

PHCVPRDLSWLDLEANMCLP
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

產(chǎn)品名稱：
R18
目錄號：
HY-P1039
需求量：