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  2. 天然產(chǎn)物
  3. 疾病研究領(lǐng)域 植物 黃酮類 酚類
  4. 香蒲科 心血管 黃酮醇 多酚類
  5. 蒲黃
  6. Isorhamnetin 3-O-galactoside

Isorhamnetin 3-O-galactoside  (Synonyms: 異鼠李素-3-O-半乳糖苷; Cacticin)

目錄號: HY-N2082 純度: 99.64%
COA 產(chǎn)品使用指南 技術(shù)支持

Isorhamnetin 3-O-galactoside (Cacticin) 是從 Artemisia capillaris Thunberg 中分離出的一種黃酮苷，通過增強(qiáng)抗氧化防御系統(tǒng)和減少炎癥信號通路來改善 CCl4-誘導(dǎo)的肝損傷。Isorhamnetin 3-O-galactoside (Cacticin) 具有抗血栓和抗炎作用。

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Isorhamnetin 3-O-galactoside Chemical Structure

Isorhamnetin 3-O-galactoside Chemical Structure

CAS No. : 6743-92-6

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥1200
In-stock
5 mg ￥3200
In-stock
10 mg ￥5200
In-stock
50 mg   詢價  
100 mg   詢價  

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MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻(xiàn)

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Isorhamnetin 3-O-galactoside (Cacticin), a flavonoid glycoside isolated from Artemisia capillaris Thunberg, which ameliorates CCl4-induced hepatic damage by enhancing the anti-oxidative defense system and reducing the inflammatory signaling pathways. Isorhamnetin 3-O-galactoside (Cacticin) has antithrombotic and anti-inflammatory activities[1][2][3].

細(xì)胞效力
(Cellular Effect)
Cell Line Type Value Description References
BMDC IC50
> 50 μM
Compound: 11
Inhibition of LPS-induced IL-12 p40 production in wild-type C57BL/6 mouse BMDC pretreated with compound for 1 hr before LPS treatment measured 16 hrs by ELISA
Inhibition of LPS-induced IL-12 p40 production in wild-type C57BL/6 mouse BMDC pretreated with compound for 1 hr before LPS treatment measured 16 hrs by ELISA
[PMID: 25769817]
BMDC IC50
> 50 μM
Compound: 11
Inhibition of LPS-induced IL-6 production in wild-type C57BL/6 mouse BMDC pretreated with compound for 1 hr before LPS treatment measured 16 hrs by ELISA
Inhibition of LPS-induced IL-6 production in wild-type C57BL/6 mouse BMDC pretreated with compound for 1 hr before LPS treatment measured 16 hrs by ELISA
[PMID: 25769817]
BMDC IC50
> 50 μM
Compound: 11
Inhibition of LPS-induced TNF-alpha production in wild-type C57BL/6 mouse BMDC pretreated with compound for 1 hr before LPS treatment measured 16 hrs by ELISA
Inhibition of LPS-induced TNF-alpha production in wild-type C57BL/6 mouse BMDC pretreated with compound for 1 hr before LPS treatment measured 16 hrs by ELISA
[PMID: 25769817]
C2C12 EC50
18.5 μM
Compound: 6
Increase in glucose uptake in mouse C2C12 cells incubated for 18 hrs using [3H]-2-deoxy-D-glucose by liquid scintillation counting
Increase in glucose uptake in mouse C2C12 cells incubated for 18 hrs using [3H]-2-deoxy-D-glucose by liquid scintillation counting
[PMID: 22738356]
Monocyte IC50
3.8 μM
Compound: isorhamnetin 3-glucoside
Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression after 18 hrs
Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression after 18 hrs
[PMID: 8882428]
分子量

478.40

Formula

C22H22O12
CAS 號
性狀

固體

顏色

Light yellow to yellow

中文名稱

異鼠李素-3-O-半乳糖苷
結(jié)構(gòu)分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性數(shù)據(jù)
細(xì)胞實驗： 

DMSO 中的溶解度 : 100 mg/mL (209.03 mM; 超聲助溶; 吸濕的 DMSO 對產(chǎn)品的溶解度有顯著影響，請使用新開封的 DMSO)

配制儲備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 2.0903 mL 10.4515 mL 20.9030 mL
5 mM 0.4181 mL 2.0903 mL 4.1806 mL
查看完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲存時，請在6個月內(nèi)使用，-20°C儲存時，請在1個月內(nèi)使用。

  • 摩爾計算器

  • 稀釋計算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動物溶解方案計算器
請輸入動物實驗的基本信息：

給藥劑量

mg/kg

動物的平均體重

g

每只動物的給藥體積

μL

動物數(shù)量

只
由于實驗過程有損耗，建議您多配一只動物的量
計算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料

純度: 99.64%

參考文獻(xiàn)

完整儲備液配制表

* 請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲存時，請在6個月內(nèi)使用，-20°C儲存時，請在1個月內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0903 mL 10.4515 mL 20.9030 mL 52.2575 mL
5 mM 0.4181 mL 2.0903 mL 4.1806 mL 10.4515 mL
10 mM 0.2090 mL 1.0452 mL 2.0903 mL 5.2258 mL
15 mM 0.1394 mL 0.6968 mL 1.3935 mL 3.4838 mL
20 mM 0.1045 mL 0.5226 mL 1.0452 mL 2.6129 mL
25 mM 0.0836 mL 0.4181 mL 0.8361 mL 2.0903 mL
30 mM 0.0697 mL 0.3484 mL 0.6968 mL 1.7419 mL
40 mM 0.0523 mL 0.2613 mL 0.5226 mL 1.3064 mL
50 mM 0.0418 mL 0.2090 mL 0.4181 mL 1.0452 mL
60 mM 0.0348 mL 0.1742 mL 0.3484 mL 0.8710 mL
80 mM 0.0261 mL 0.1306 mL 0.2613 mL 0.6532 mL
100 mM 0.0209 mL 0.1045 mL 0.2090 mL 0.5226 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Isorhamnetin 3-O-galactoside
目錄號：
HY-N2082
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