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  2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Flavin adenine dinucleotide

Flavin adenine dinucleotide  (Synonyms: 黃素腺嘌呤二核苷酸; FAD)

目錄號: HY-B1654 純度: 99.13%
COA 產品使用指南

Flavin adenine dinucleotide (FAD) 是一種氧化還原輔因子，蛋白質的輔基，在代謝過程中參與了幾個重要的酶反應。

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Flavin adenine dinucleotide Chemical Structure

Flavin adenine dinucleotide Chemical Structure

CAS No. : 146-14-5

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規(guī)格 價格 是否有貨 數量
5 mg ￥500
In-stock
10 mg ￥750
In-stock
50 mg   詢價  
100 mg   詢價  

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Customer Review

Other Forms of Flavin adenine dinucleotide:

  • 生物活性

  • 實驗參考方法

  • 純度 & 產品資料

  • 參考文獻

生物活性

Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

IC50 & Target

Human Endogenous Metabolite

 

體外研究
(In Vitro)

Poly(Flavin adenine dinucleotide, FAD) characterized by an additional polymer-type redox reaction is a highly effective electrocatalyst for NADH oxidation: operating at the lowest potentials reported for NADH transducers (0.00 V, pH 7.4), poly(FAD) is characterized by the electrochemical rate constant of 1.8 ± 0.6×10-3 cm/s, which is at the level of the NADH mass-transfer constant. Poly(FAD)-modified electrodes are characterized by the dramatically improved stability and, is the most advantageous NADH transducers for analytical chemistry[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
體內研究
(In Vivo)

Flavin adenine dinucleotide (2 mg/kg, i.v.) significantly cancels chlorpromazine (CPZ)-induced decrease in ventricular fibrillation threshold (VFT). Flavin adenine dinucleotide cancels the effect of CPZ on canine heart mitochondria. After injection of Flavin adenine dinucleotide, the dogs show a transient hypotension within 10 min, then their blood pressures recover to the initial level. Flavin adenine dinucleotide also prevents mitochondrial dysfunction induced by chlorpromazine[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

785.55

Formula

C27H33N9O15P2
CAS 號
性狀

固體

顏色

Yellow to orange

中文名稱

黃素腺嘌呤二核苷酸
結構分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性數據
細胞實驗： 

H2O 中的溶解度 : 125 mg/mL (159.12 mM; 超聲助溶)

配制儲備液
濃度 溶劑體積 質量 1 mg 5 mg 10 mg
1 mM 1.2730 mL 6.3650 mL 12.7299 mL
5 mM 0.2546 mL 1.2730 mL 2.5460 mL
查看完整儲備液配制表

* 請根據產品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復凍融造成的產品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲存時，請在6個月內使用，-20°C儲存時，請在1個月內使用。

* 備注：如您選擇水作為儲備液，請稀釋至工作液后，再用 0.22 μm 的濾膜過濾除菌后使用。

  • 摩爾計算器

  • 稀釋計算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動物溶解方案計算器
請輸入動物實驗的基本信息：

給藥劑量

mg/kg

動物的平均體重

g

每只動物的給藥體積

μL

動物數量

只
由于實驗過程有損耗，建議您多配一只動物的量
計算結果
工作液所需濃度 : mg/mL
該產品水溶性佳，請具體參考實測 水 / PBS / Saline 中的溶解度數據。
您所需的儲備液濃度超過該產品的實測溶解度，如有需要，請與 MCE 中國技術支持聯系。
純度 & 產品資料

純度: 99.13%

參考文獻
Animal Administration
[1]

Dogs[1]
The dogs are divided into 3 groups and they are received the following treatments. Each group consists of 6 dogs. Dogs in group I as control, are given 2 mL/kg of physiological saline by intravenous injection. Ten min after the start of the first injection, another dose of saline, 1 mL/kg, is injected intravenously. Dogs in group II are given i.v. 2 mL saline/kg. Ten min afterwards, 1 mg chlorpromazine(CPZ)/kg is injected. Dogs in group III are given i.v. Flavin Adenin Dinucleotide, 2 mg/kg. Ten min later, they are given CPZ, 1 mg/kg. All solutions is administrated in 1 min or 2. Blood samples are taken before and 10, 20, 30, and 40 min after the intravenous injection of saline (groups I and II) or Flavin Adenin Dinucleotide (group III). Serum K+ and blood pH are also measured. Heart rate, blood pressure and ventricular fibrillation threshold (VFT) of each dog are recorded at the same intervals[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
參考文獻

完整儲備液配制表

* 請根據產品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；一旦配成溶液，請分裝保存，避免反復凍融造成的產品失效。
儲備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C儲存時，請在6個月內使用，-20°C儲存時，請在1個月內使用。

可選溶劑 濃度 溶劑體積 質量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.2730 mL 6.3650 mL 12.7299 mL 31.8248 mL
5 mM 0.2546 mL 1.2730 mL 2.5460 mL 6.3650 mL
10 mM 0.1273 mL 0.6365 mL 1.2730 mL 3.1825 mL
15 mM 0.0849 mL 0.4243 mL 0.8487 mL 2.1217 mL
20 mM 0.0636 mL 0.3182 mL 0.6365 mL 1.5912 mL
25 mM 0.0509 mL 0.2546 mL 0.5092 mL 1.2730 mL
30 mM 0.0424 mL 0.2122 mL 0.4243 mL 1.0608 mL
40 mM 0.0318 mL 0.1591 mL 0.3182 mL 0.7956 mL
50 mM 0.0255 mL 0.1273 mL 0.2546 mL 0.6365 mL
60 mM 0.0212 mL 0.1061 mL 0.2122 mL 0.5304 mL
80 mM 0.0159 mL 0.0796 mL 0.1591 mL 0.3978 mL
100 mM 0.0127 mL 0.0636 mL 0.1273 mL 0.3182 mL

* 備注：如您選擇水作為儲備液，請稀釋至工作液后，再用 0.22 μm 的濾膜過濾除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產品名稱：
Flavin adenine dinucleotide
目錄號：
HY-B1654
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