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  2. Anti-infection Cell Cycle/DNA Damage
  3. Bacterial Antibiotic DNA/RNA Synthesis
  4. Cinoxacin

Cinoxacin  (Synonyms: 西諾沙星; Compound 64716)

目錄號(hào): HY-B1085 純度: 99.99%
COA 產(chǎn)品使用指南

Cinoxacin (Compound 64716)，一種與喹諾酮類抗生素相關(guān)的口服抗菌劑。Cinoxacin 對(duì)許多革蘭氏陰性需氧菌 (Gram-negative aerobic bacteria) 具有抗菌活性，并抑制細(xì)菌 DNA 的合成。Cinoxacin 可用于尿路感染和細(xì)菌性前列腺炎的研究。

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Cinoxacin Chemical Structure

Cinoxacin Chemical Structure

CAS No. : 28657-80-9

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規(guī)格 價(jià)格 是否有貨 數(shù)量
10 mM * 1 mL in DMSO ￥282
In-stock
25 mg ￥256
In-stock
50 mg ￥400
In-stock
100 mg ￥640
In-stock
200 mg   詢價(jià)  
500 mg   詢價(jià)  

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Customer Review

Other Forms of Cinoxacin:

MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻(xiàn)

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis[1][2].

IC50 & Target

Quinolone

 

體外研究
(In Vitro)

Cinoxacin (0-200μg/mL approximately, 3-24 h) inhibits many gram-negative aerobic bacteria with MIC values ranging from 4 to 64 μg/mL[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[2]

Cell Line: Gram-negative aerobic bacteria (Escherichia coli, Proteus sp. etc.)
Concentration: 0-200μg/mL approximately
Incubation Time: 3-24 h
Result: Inhibited basal cell proliferation (40% in FB-2 and 35% in WRO) at 10 μM, inhibited cell number (by 68% to 73%) at 40 and 60 μM).
體內(nèi)研究
(In Vivo)

Cinoxacin (Oral administration, 1.7 g/kg, treated at 1 and 5 h postinfection) is effective in experimental bacterial infections in mice, with ED50 values ranging from 8.1 to 58.6 mg/kg[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Indicated bacterial infected mice model[2]
Dosage: 1.7 g/kg, treated at 1 and 5 h postinfection
Administration: Oral administration
Result: Displayed antibacterial activity with ED50 values ranging from 8.1 to 58.6 mg/kg.
分子量

262.22

Formula

C12H10N2O5
CAS 號(hào)
性狀

固體

顏色

White to off-white

中文名稱

西諾沙星
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
溶解性數(shù)據(jù)
細(xì)胞實(shí)驗(yàn)： 

DMSO 中的溶解度 : 8.33 mg/mL (31.77 mM; 超聲助溶; 吸濕的 DMSO 對(duì)產(chǎn)品的溶解度有顯著影響，請(qǐng)使用新開封的 DMSO)

配制儲(chǔ)備液
濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg
1 mM 3.8136 mL 19.0680 mL 38.1359 mL
5 mM 0.7627 mL 3.8136 mL 7.6272 mL
查看完整儲(chǔ)備液配制表

* 請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；一旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?年內(nèi)使用， -20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?年內(nèi)使用。

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動(dòng)物溶解方案計(jì)算器
請(qǐng)輸入動(dòng)物實(shí)驗(yàn)的基本信息：

給藥劑量

mg/kg

動(dòng)物的平均體重

g

每只動(dòng)物的給藥體積

μL

動(dòng)物數(shù)量

只
由于實(shí)驗(yàn)過程有損耗，建議您多配一只動(dòng)物的量
計(jì)算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料

純度: 99.99%

參考文獻(xiàn)

完整儲(chǔ)備液配制表

* 請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；一旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?年內(nèi)使用， -20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?年內(nèi)使用。

可選溶劑 濃度 溶劑體積 質(zhì)量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8136 mL 19.0680 mL 38.1359 mL 95.3398 mL
5 mM 0.7627 mL 3.8136 mL 7.6272 mL 19.0680 mL
10 mM 0.3814 mL 1.9068 mL 3.8136 mL 9.5340 mL
15 mM 0.2542 mL 1.2712 mL 2.5424 mL 6.3560 mL
20 mM 0.1907 mL 0.9534 mL 1.9068 mL 4.7670 mL
25 mM 0.1525 mL 0.7627 mL 1.5254 mL 3.8136 mL
30 mM 0.1271 mL 0.6356 mL 1.2712 mL 3.1780 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Cinoxacin
目錄號(hào)：
HY-B1085
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