4 | 3β-Hydroxy-5-pregnen-20-one-d4 | 孕烯醇酮 d4 | Cannabinoid Receptor | TRP Channel | Endogenous Metabolite | Autophagy | Transient receptor potential channels | Inhibitor | inhibitor | inhibit"/>

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  2. GPCR/G Protein Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease Autophagy
  3. Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
  4. Pregnenolone-d4

Pregnenolone-d4  (Synonyms: 3β-Hydroxy-5-pregnen-20-one-d4)

目錄號(hào): HY-B0151S
產(chǎn)品使用指南 技術(shù)支持

Pregnenolone-d4 是 Pregnenolone 的氘代物。Pregnenolone (3β-Hydroxy-5-pregnen-20-one) 是一種功能強(qiáng)大的神經(jīng)甾體，是包括甾體酮在內(nèi)的各種甾體激素的主要前體。Pregnenolone 是大麻素 CB1 受體的信號(hào)傳導(dǎo)特異性抑制劑，抑制由 CB1 受體介導(dǎo)的四氫大麻酚 (THC) 的作用。Pregnenolone 可以保護(hù)大腦免受大麻中毒。Pregnenolone 也是一種 TRPM3 通道激活劑，也可以弱激活 TRPM1 通道。

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Pregnenolone-d<sub>4</sub> Chemical Structure

Pregnenolone-d4 Chemical Structure

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規(guī)格 價(jià)格 是否有貨 數(shù)量
1 mg ￥3500
1 - 2 周
5 mg   詢價(jià)  
10 mg   詢價(jià)  

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Customer Review

Other Forms of Pregnenolone-d4:

MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻(xiàn)

查看 Cannabinoid Receptor 亞型特異性產(chǎn)品:

查看 TRP Channel 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Pregnenolone-d4 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

體外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

320.50

Formula

C21H28D4O2
非標(biāo)記 CAS
中文名稱

孕烯醇酮 d4
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Pregnenolone-d4
目錄號(hào)：
HY-B0151S
需求量：