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  2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Arformoterol tartrate

Arformoterol tartrate  (Synonyms: 酒石酸福莫特羅; (R,R)-Formoterol tartrate)

目錄號(hào): HY-B0010D
產(chǎn)品使用指南 技術(shù)支持

Arformoterol ((R,R)-Formoterol) tartrate 是 Formoterol 的 (R,R)-對(duì)映異構(gòu)體，是一種長(zhǎng)效 β2-腎上腺素能受體 (β2-AR) 激動(dòng)劑，Kd 為 2.9 nM。Arformoterol tartrate 可用于慢性阻塞性肺疾病 (COPD) 的研究。

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Arformoterol tartrate Chemical Structure

Arformoterol tartrate Chemical Structure

CAS No. : 200815-49-2

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規(guī)格 價(jià)格 是否有貨 數(shù)量
5 mg ￥811
1 - 2 周
10 mg   詢價(jià)  
50 mg   詢價(jià)  

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Customer Review

Other Forms of Arformoterol tartrate:

MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻(xiàn)

查看 Adrenergic Receptor 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Arformoterol ((R,R)-Formoterol) tartrate, the (R,R)-enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a Kd of 2.9 nM. Arformoterol tartrate can be used for the research of chronic obstructive pulmonary disease (COPD)[1][2].

IC50 & Target[1]

Beta-2 adrenergic receptor

2.9 nM (Kd)

體外研究
(In Vitro)

Arformoterol tartrate induces cAMP accumulation in cultured human bronchial epithelial cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
體內(nèi)研究
(In Vivo)

Arformoterol tartrate (10 ng in 0.1 ml saline/20 g body weight; intranasal instillation) mitigates Cl2-induced increases of respiratory system resistance and elastance in mice[3].
Arformoterol tartrate reverses histamine- and ovalbumin-induced bronchoconstriction in guinea pigs (ED50s=1 and 40 nmol/kg, respectively)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wild-type and iNOS?/? mice were exposed to Cl2 gas[3]
Dosage: 10 ng in 0.1 ml saline/20 g body weight
Administration: Intranasal instillation in the external nares at 10 minutes and every 24 hours after exposure
Result: Significantly mitigated the Cl2-induced increases of respiratory system resistance and elastance.
Increased cAMP in the lungs of Cl2-exposed mice.
Not mitigated Cl2-induced lung injury and inflammation.
分子量

494.49

Formula

C23H30N2O10
CAS 號(hào)
中文名稱

酒石酸福莫特羅
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

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  • 稀釋計(jì)算器

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Arformoterol tartrate
目錄號(hào)：
HY-B0010D
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