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  2. Anti-infection
  3. Antibiotic Bacterial
  4. Gentamicin

Gentamicin 是一種具有口服活性的氨基糖苷類抗生素，抑制革蘭氏陽性菌和革蘭氏陰性細菌的生長并可抑制組織培養(yǎng)中的多種支原體菌株。Gentamicin 抑制 DNase I 活性的 IC50 值為 0.57 mM。

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Gentamicin Chemical Structure

Gentamicin Chemical Structure

CAS No. : 1403-66-3

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5 mg ￥350
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10 mg ￥550
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25 mg ￥1100
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50 mg ￥1750
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100 mg ￥2800
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500 mg   詢價  

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Customer Review

Other Forms of Gentamicin:

MCE 顧客使用本產(chǎn)品發(fā)表的 35 篇科研文獻

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Gentamicin, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin inhibits DNase I with an IC50 of 0.57 mM[1][2][3][4].

IC50 & Target

Aminoglycoside

 

體外研究
(In Vitro)

Gentamicin is a more effective in vitro bacterial inhibitor than combined penicillin-streptomycin, is nontoxic to tissue culture monolayers, and does not inhibit virus replication[2].
Gentamicin has been used with success as an additive in commercial mycology media to inhibit growth of bacteria and has been shown to be bactericidal for a wider range of organisms (Pseudomonas aeruginosa, Proteus sp., and Streptococcus faecalis) than penicillin and streptomycin[2].
Gentamicin does not interfere with the production of cytopathic effect by certain echoviruses and polioviruses in tissue culture, is nontoxic to Rhesus monkey kidney, HeLa, and human amnion cells, and is stable at autoclave temperatures[2].
Gentamicin is produced by various species of the genus Micromonospora[3].
Gentamicin C1a binds in the major groove of the A-site of the RNA[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
體內(nèi)研究
(In Vivo)

Gentamicin (oral and injectable forms) exhibits effective antibacterial activity against Yersinia pestis as demonstrated in a mouse infection model[3].
Gentamicin (0.27 g/kg) shows a significant reduction of bacteria on the foreign body in mouse[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Formula

C24H53N7O73*
CAS 號
性狀

固體

顏色

White to light yellow

運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶解性數(shù)據(jù)
細胞實驗： 

H2O 中的溶解度 : 175 mg/mL (超聲助溶)

  • 摩爾計算器

  • 稀釋計算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動物溶解方案計算器
請輸入動物實驗的基本信息：

給藥劑量

mg/kg

動物的平均體重

g

每只動物的給藥體積

μL

動物數(shù)量

只
由于實驗過程有損耗，建議您多配一只動物的量
計算結果
工作液所需濃度 : mg/mL
該產(chǎn)品水溶性佳，請具體參考實測 水 / PBS / Saline 中的溶解度數(shù)據(jù)。
您所需的儲備液濃度超過該產(chǎn)品的實測溶解度，如有需要，請與 MCE 中國技術支持聯(lián)系。
純度 & 產(chǎn)品資料
參考文獻

Gentamicin 相關分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Gentamicin
目錄號：
HY-A0276A
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