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  1. Vitamin D Related/Nuclear Receptor
  2. Thyroid Hormone Receptor
  3. Liothyronine

Liothyronine  (Synonyms: 三碘甲狀腺原氨酸; Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3)

目錄號: HY-A0070AG
產(chǎn)品使用指南 技術(shù)支持

Liothyronine (Triiodothyronine) (GMP) 是 GMP 級別的 Liothyronine (HY-A0070A)。GMP 級別的小分子可用做細(xì)胞療法中的輔助試劑。Liothyronine 是有效的 TRαTRβ 激動劑,對 hTRα 和 hTRβ 的 Ki 值均為 2.33 nM。

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Liothyronine Chemical Structure

Liothyronine Chemical Structure

CAS No. : 6893-02-3

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  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Liothyronine (Triiodothyronine) (GMP) is the Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1].

IC50 & Target

TRβ1[1][2]

體外研究
(In Vitro)

Liothyronine (GMP) 可用于誘導(dǎo)人角質(zhì)形成細(xì)胞生成誘導(dǎo)性多能干細(xì)胞[1]
Liothyronine (GMP) 是角膜緣干細(xì)胞 (LSC) 增殖和自我更新所必需的[2]。
Liothyronine (GMP) (4 nM) 促進(jìn)胚胎干細(xì)胞的心臟分化和成熟[3]
Liothyronine (GMP) (100 nM,14 天) 促進(jìn)人誘導(dǎo)多能干細(xì)胞 (hiPSC) 來源的心肌細(xì)胞的電生理成熟[4]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

650.97

Formula

C15H12I3NO4

CAS 號
性狀

固體

顏色

White to off-white

中文名稱

三碘甲狀腺原氨酸 (GMP); 碘噻羅寧 (GMP)

運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

純度 & 產(chǎn)品資料
參考文獻(xiàn)
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  • 稀釋計算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱:
Liothyronine
目錄號:
HY-A0070AG
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