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  2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. XAV-939

XAV-939 (GMP) 是 GMP 級別的 XAV-939 (HY-15147)。GMP 級別的小分子可用做細胞療法中的輔助試劑。XAV-939 是一種 tankyrase 抑制劑。

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XAV-939 Chemical Structure

XAV-939 Chemical Structure

CAS No. : 284028-89-3

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規(guī)格 價格 是否有貨 數(shù)量
10 mg ￥8640
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  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

XAV-939 (GMP) is XAV-939 (HY-15347) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. XAV-939 is a tankyrase inhibitor[1].

體外研究
(In Vitro)

XAV-939 (GMP) (5 μM; 2 μM for 3 days; 1 μM) induces human pluripotent stem cells (hPSCs) to post-mitotic cortical neurons differentiation[1].
XAV939 (GMP) promotes anterior CNS identity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

RT-PCR[1]

Cell Line: Human pluripotent stem cells (hPSCs)
Concentration: 5 μM, 2 μM, 1 μM
Incubation Time: 3 days
Result: Showed downregulation of the pluripotency marker OCT4 and induction of neural and neuronal markers PAX6, FOXG1 and DCX, as well as markers of early born cortical neurons, including TBR1 (preplate, subplate and layer VI) and REELIN, in LSB+X/P/S/D conditions.
分子量

312.31

Formula

C14H11F3N2OS
CAS 號
性狀

固體

顏色

White to off-white

運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻

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質(zhì)量   濃度   體積   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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  • Do most proteins show cross-species activity?

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產(chǎn)品名稱：
XAV-939
目錄號：
HY-15147G
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