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  2. Stem Cell/Wnt
  3. Smo
  4. Purmorphamine

Prostaglandin E2 (GMP) 是 GMP 級別的 Prostaglandin E2 (HY-15108)。GMP 級別的小分子可用做細胞療法中的輔助試劑。Purmorphamine 是一種平滑受體 (smoothened/Smo receptor) 激動劑，EC50 為 1 μM。

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Purmorphamine Chemical Structure

Purmorphamine Chemical Structure

CAS No. : 483367-10-8

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規(guī)格 價格 是否有貨 數(shù)量
10 mg ￥11520
In-stock
50 mg ￥34560
In-stock
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200 mg   詢價  

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MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Purmorphamine (GMP) is Purmorphamine (HY-15108) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Purmorphamine is a smoothened/Smo receptor agonist with an EC50 of 1 μM[1].

體外研究
(In Vitro)

Purmorphamine (GMP) (1.5 μM, 1 week) can generate embryoid bodies (EBs) from human iPS cells (hiPS2) and hESCs (HSF1)[1].
Purmorphamine (GMP) (1.5 μM) converts hPSCs to NKX2-1 positive MGE cells[2].
Purmorphamine (GMP) (2 μM, day 28-35) promotes ventralization of the brain spheroids in differentiation process from hiPSCs[3].
Purmorphamine (GMP) (1 μM) together with retinoic acid (RA, 2 μM) promotes hiPSC differentiation into functional neural tissue, indicated by the expression of neuronal marker β-tubulin III (βT-III)[4].
Purmorphamine (GMP) (day5-7) induces hESCs differentiation into dopaminergic (DA) neurons[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

520.62

Formula

C31H32N6O2
CAS 號
性狀

固體

顏色

Off-white to pale purple

運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻

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  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   體積   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Purmorphamine
目錄號：
HY-15108G
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