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  2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. m-PEG10-alcohol

m-PEG10-alcohol  (Synonyms: Decaethylene glycol monomethyl ether)

目錄號: HY-141218
COA 產(chǎn)品使用指南

m-PEG10-alcohol (Decaethylene glycol monomethyl ether) 是一種不可降解 (non-cleavable) 的含 10 個單元 PEG 的 ADC linker，可用于合成抗體偶聯(lián)活性分子 (ADC)。m-PEG10-alcohol 還是一種 PROTAC linker，屬于 PEG 類，可用于合成 PROTAC 分子。

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m-PEG10-alcohol Chemical Structure

m-PEG10-alcohol Chemical Structure

CAS No. : 27425-92-9

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規(guī)格 價格 是否有貨
250 mg ￥100
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500 mg ￥150
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1 g ￥270
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  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG10-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

Non-cleavable Linker

 

體外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

472.57

Formula

C21H44O11
CAS 號
性狀

固液混合物

顏色

Colorless to light yellow

運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: ≥97.0%

參考文獻(xiàn)

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

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產(chǎn)品名稱：
m-PEG10-alcohol
目錄號：
HY-141218
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