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  2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. β-D-Glucan

β-D-Glucan  (Synonyms: β-D-葡聚糖)

目錄號(hào): HY-139413 純度: ≥98.0%
COA 產(chǎn)品使用指南 技術(shù)支持

β-D-glucan 是一種天然的不易消化的多糖，具有很高的生物相容性，可被識(shí)別受體，如 Dectin-1 和 Toll 樣受體選擇性識(shí)別，并容易被鼠或人巨噬細(xì)胞內(nèi)化。β-D-glucan 是益生菌的腸道輸送載體。

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β-D-Glucan Chemical Structure

β-D-Glucan Chemical Structure

CAS No. : 9041-22-9

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規(guī)格 價(jià)格 是否有貨 數(shù)量
5 mg ￥312
In-stock
10 mg ￥500
In-stock
25 mg ￥800
In-stock
50 mg   詢(xún)價(jià)  
100 mg   詢(xún)價(jià)  

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Customer Review

查看 Toll-like Receptor (TLR) 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery[1]. β-d-glucan is an enteric delivery vehicle for probiotics[2].

體外研究
(In Vitro)

β-D-glucan dissolved in DMSO but not water inhibits MCF-7 cell proliferation in a concentration-dependent manner as measured by BrdU incorporation with an IC50 of ～164 μg/mL. β-D-glucan dissolved in DMSO inhibits tamoxifen/endocrine-resistant LCC9 and LY2 cell proliferation with IC50 values of 4.6 and 24.2 μg/mL, respectively[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS 號(hào)
性狀

固體

顏色

White to light yellow

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性數(shù)據(jù)
細(xì)胞實(shí)驗(yàn)： 

1M NaOH 中的溶解度 : 50 mg/mL (超聲助溶; 堿性條件溶解 (NaOH 調(diào)節(jié)，pH≈11))

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動(dòng)物溶解方案計(jì)算器
請(qǐng)輸入動(dòng)物實(shí)驗(yàn)的基本信息：

給藥劑量

mg/kg

動(dòng)物的平均體重

g

每只動(dòng)物的給藥體積

μL

動(dòng)物數(shù)量

只
由于實(shí)驗(yàn)過(guò)程有損耗，建議您多配一只動(dòng)物的量
計(jì)算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料

純度: ≥98.0%

參考文獻(xiàn)
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱(chēng)：
β-D-Glucan
目錄號(hào)：
HY-139413
需求量：