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  4. 9-cis-β-Carotene

9-cis-β-Carotene 一種視網(wǎng)膜的前體 (precursor)，由 β-胡蘿卜素加氧酶 1 (BCMO1) 裂解產(chǎn)生 9-cis-retinal。9-cis-β-Carotene 在動物模型中抑制視網(wǎng)膜光感受器變性和幫助恢復(fù)視網(wǎng)膜功能。9-cis-β-Carotene 有潛力用于先天性靜止夜盲癥的研究。

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9-cis-β-Carotene Chemical Structure

9-cis-β-Carotene Chemical Structure

CAS No. : 13312-52-2

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規(guī)格 價格 是否有貨 數(shù)量
500 μg ￥13500
1 - 2 周

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Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. 9-cis-β-Carotene inhibits photoreceptor degeneration and restores retinal function in vivo. 9-cis-β-Carotene has the potential for the study of congenital stationary night blindness and fundus albipunctatus[1].
體外研究
(In Vitro)

9-cis-β-Carotene (1 μM; 18 hours) formulates with the Miglyol 810 and the“antioxidant mix” is incubated to eye cups. The eye cups are isolated from the neuro-retina attached to the underlying RPE tissue from?RPE65rd12 mouse. It prevents S- and M-cones degeneration and leads to over 2- and 9- fold higher m-opsin and s-opsin positive staining compares to the control group[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
體內(nèi)研究
(In Vivo)

In a mouse model of retinoid cycle defect, RPE65rd12. Mice with an extract of?Dunaliella Bardawil?algae rich in 9-cis-β-Carotene (9CBC) rescues retinal function and preserves cone structure by oral administration[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

536.87

Formula

C40H56
CAS 號
性狀

固體

顏色

Light brown to brown

運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻

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產(chǎn)品名稱：
9-cis-β-Carotene
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