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  2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Aminooxy-amido-PEG4-propargyl

Aminooxy-amido-PEG4-propargyl 

目錄號: HY-133435 純度: ≥97.0%
COA 產(chǎn)品使用指南 技術(shù)支持

Aminooxy-amido-PEG4-propargyl 是一種不可降解 (non-cleavable) 的含 4 個單元 PEG 的 ADC linker，可用于合成抗體偶聯(lián)活性分子 (ADC)。Aminooxy-amido-PEG4-propargyl 是一種點擊化學(xué)試劑。它含有 Alkyne 基團(tuán)，可以和含有 Azide 基團(tuán)的分子發(fā)生銅催化的疊氮-炔環(huán)加成反應(yīng) (CuAAc)。

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Aminooxy-amido-PEG4-propargyl Chemical Structure

Aminooxy-amido-PEG4-propargyl Chemical Structure

CAS No. : 2253965-03-4

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規(guī)格 價格 是否有貨 數(shù)量
50 mg ￥720
In-stock
100 mg ￥1136
In-stock
250 mg ￥1902
詢價
1 g ￥5498
詢價
5 g   詢價  
10 g   詢價  

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  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

Non-cleavable Linker

 

體外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

304.34

Formula

C13H24N2O6
CAS 號
性狀

粘稠液體

顏色

Colorless to light yellow

運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

純度 & 產(chǎn)品資料
參考文獻(xiàn)

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產(chǎn)品名稱：
Aminooxy-amido-PEG4-propargyl
目錄號：
HY-133435
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