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  1. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  2. Reactive Oxygen Species
  3. Decylubiquinone

Decylubiquinone  (Synonyms: 癸基泛醌)

目錄號(hào): HY-121134 純度: ≥99.0%
COA 產(chǎn)品使用指南

Decylubiquinone 是泛醌 (輔酶 Q10) 的類似物。Decylubiquinone 阻止活性氧 (ROS) 的產(chǎn)生以響應(yīng)谷胱甘肽消耗并抑制線粒體通透性轉(zhuǎn)變的激活。

MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報(bào),我們不為任何個(gè)人用途提供產(chǎn)品和服務(wù)

Decylubiquinone Chemical Structure

Decylubiquinone Chemical Structure

CAS No. : 55486-00-5

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規(guī)格 價(jià)格 是否有貨 數(shù)量
5mg (77.53 mM * 200 μL in Ethanol) ¥1400
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10mg (77.53 mM * 400 μL in Ethanol) ¥2200
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  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Decylubiquinone is an analog of ubiquinone (coenzyme Q10). Decylubiquinone blocks reactive oxygen species (ROS) production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition[1].

體外研究
(In Vitro)

Decylubiquinone (dUb; 10 μm for 6 hours) exerts its effects on ROS by either inhibition of ROS production by cytochrome bc1 or that it scavenged ROS produced[1].
Decylubiquinone inhibits both the dichlorofluorescein (DCF) fluorescence increase resulting from H2O2 treatment and the DCF fluorescence increase resulting after glutathione (GSH) depletion using diethylmaleate mitochondrially generated ROS)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: HL60 cells transfected with bcl-2 (bcl-2) (HL60 B cells)
Concentration: 10 μM
Incubation Time: 6 hours
Result: Attenuated the ROS increase in HL60 (B) cells.
分子量

322.44

Formula

C19H30O4

CAS 號(hào)
性狀

液體

顏色

Yellow to brown

中文名稱

癸基泛醌

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式

Solution, -20°C, 2 years

純度 & 產(chǎn)品資料

純度: ≥99.0%

參考文獻(xiàn)
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產(chǎn)品名稱:
Decylubiquinone
目錄號(hào):
HY-121134
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