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  2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. Amino-Tri-(carboxyethoxymethyl)-methane

Amino-Tri-(carboxyethoxymethyl)-methane 

目錄號(hào): HY-117519 純度: ≥98.0%
COA 產(chǎn)品使用指南 技術(shù)支持

Amino-Tri-(carboxyethoxymethyl)-methan 是一種可降解 (cleavable) 的 PEG 的 ADC linker，可用于合成抗體偶聯(lián)藥物 (ADC)。Amino-Tri-(carboxyethoxymethyl)-methan 也是一種 PROTAC linker，屬于 PEG 類，可用于合成 PROTAC 分子。

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Amino-Tri-(carboxyethoxymethyl)-methane Chemical Structure

Amino-Tri-(carboxyethoxymethyl)-methane Chemical Structure

CAS No. : 174362-95-9

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規(guī)格 價(jià)格 是否有貨 數(shù)量
25 mg ￥660
In-stock
50 mg ￥990
In-stock
100 mg ￥1951
In-stock
250 mg ￥3509
In-stock
500 mg ￥4918
In-stock
1 g 現(xiàn)貨 詢價(jià)
5 g   詢價(jià)  
10 g   詢價(jià)  

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Other Forms of Amino-Tri-(carboxyethoxymethyl)-methane:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Amino-Tri-(carboxyethoxymethyl)-methane is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-Tri-(carboxyethoxymethyl)-methan is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

IC50 & Target[1][2]

PEGs

 

Cleavable Linker

 

體外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

337.32

Formula

C13H23NO9
CAS 號(hào)
性狀

固液混合物

顏色

Colorless to off-white

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

純度 & 產(chǎn)品資料

純度: ≥98.0%

參考文獻(xiàn)

Amino-Tri-(carboxyethoxymethyl)-methane 相關(guān)分類

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Amino-Tri-(carboxyethoxymethyl)-methane
目錄號(hào)：
HY-117519
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