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  2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. TRPV4 agonist-1

TRPV4 agonist-1 是一種瞬時受體電位香草酸亞型 4 (TRPV4) 激動劑，在 hTRPV4 Ca2+ 實驗中 EC50 為 60 nM。

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TRPV4 agonist-1 Chemical Structure

TRPV4 agonist-1 Chemical Structure

CAS No. : 2314467-60-0

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TRPV4 agonist-1 的其他形式現(xiàn)貨產(chǎn)品:

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生物活性

TRPV4 agonist-1 is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay[1].

IC50 & Target

EC50: 60 nM (hTRPV4 hTRPV4 Ca2+)[1]
體外研究
(In Vitro)

TRPV4 agonist-1 (Compound 36) exhibits significantly increased potency (ECmax: 20 nM in the SOX9 reporter assay). TRPV4 agonist-1 is inactive against TRPV1 channels[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

484.93

Formula

C25H23ClF2N4O2
CAS 號
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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產(chǎn)品名稱：
TRPV4 agonist-1
目錄號：
HY-114400A
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