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  2. Anti-infection Cell Cycle/DNA Damage
  3. HIV Nucleoside Antimetabolite/Analog Antibiotic
  4. Formycin A

Formycin A (NSC 102811) 是一種嘌呤核苷抗生素，一種有效的人類(lèi)免疫缺陷病毒 1 型 (HIV-1) 的抑制劑，EC50 為 10 μM。Formycin A 顯示抗腫瘤和抗病毒活性。

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Formycin A Chemical Structure

Formycin A Chemical Structure

CAS No. : 6742-12-7

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1 mg ￥2600
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Other Forms of Formycin A:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. Formycin A shows antitumor and antiviral activities[1][2].

IC50 & Target[1]

HIV-1

10 μM (EC50)

細(xì)胞效力
(Cellular Effect)
Cell Line Type Value Description References
L1210 IC50
1 μM
Compound: formycin A
Cytotoxic concentration required to reduce rate of L1210 cell proliferation after 48 hr
Cytotoxic concentration required to reduce rate of L1210 cell proliferation after 48 hr
[PMID: 4068000]
MDCK CC50
2.6 μM
Compound: 7; FMA
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by CellTiter96 Aqueous one solution assay
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by CellTiter96 Aqueous one solution assay
[PMID: 35092894]
體外研究
(In Vitro)

Formycin A (NSC 102811; 1 μM, 5 μM, 10 μM) antagonizes Zidovudine (AZT; a dideoxynucleoside chain terminator).

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

267.24

Formula

C10H13N5O4
CAS 號(hào)
性狀

固體

顏色

White to off-white

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: ≥99.0%

參考文獻(xiàn)

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Formycin A
目錄號(hào)：
HY-102026
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