4 | 1426173-86-5 | | 西洛多辛 d4 | Isotope-Labeled Compounds | Adrenergic Receptor | Beta Receptor | Inhibitor | inhibitor | inhibit"/>

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  2. Others GPCR/G Protein Neuronal Signaling
  3. Isotope-Labeled Compounds Adrenergic Receptor
  4. Silodosin-d4

Silodosin-d4 是 Silodosin 的氘代物。Silodosin (KAD 3213; KMD 3213) 是一個(gè)強(qiáng)效的、有選擇性的、口服活性的 α1A-adrenergic receptor (α1A-AR) 阻滯劑。Silodosin 對 α1A-AR 表現(xiàn)出高度的親和力 (Ki=0.036 nM)，是 α1B-AR 和 α1D-AR 親和力的 162 和 50 倍，Ki 值分別為 21 nM 和 2.0 nM。Silodosin 是一種有效且耐受性良好的試劑，可用于 LUTS/BPH 的研究。

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Silodosin-d<sub>4</sub> Chemical Structure

Silodosin-d4 Chemical Structure

CAS No. : 1426173-86-5

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規(guī)格 價(jià)格 是否有貨 數(shù)量
1 mg ￥15379
3 - 4 周
5 mg   詢價(jià)  
10 mg   詢價(jià)  

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Other Forms of Silodosin-d4:

查看 Adrenergic Receptor 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Silodosin-d4 is the deuterium labeled Silodosin. Silodosin (KAD 3213) is a potent, selective and orally active α1A-adrenergic receptor (α1A-AR) blocker. Silodosin exhibits high affinity for α1A-AR (Ki=0.036 nM), over 162-fold and 50-fold than for α1B-AR and α1D-AR with Ki values of 21 nM and 2.0 nM, respectively. Silodosin is an effective and well-tolerated agent, it can be used for the investigation of LUTS/BPH[1][3].

體外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

499.56

Formula

C25H28D4F3N3O4
CAS 號
非標(biāo)記 CAS
中文名稱

西洛多辛 d4
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

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產(chǎn)品名稱：
Silodosin-d4
目錄號：
HY-10122S
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