NVP-BKM120 - BKM 120 | Buparlisib

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1797

CAS [944396-07-0]

MF C18H21F3N6O2
MW 410.39

Purity: 98%
Soluble in DMSO

NVP-BKM120

Description

Potent, selective, orally bioavailable class I PI3K inhibitor

CW Lindsley et al. (3-Cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu5: discovery of a new tool compound with activity in the OSS mouse model of addiction. ACS Chem. Neurosci. 2011, 2(8), 471-482.

D Koul et al. Antitumor activity of NVP-BKM120--a selective pan class I PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cells. Clin Cancer Res. 2012, 18(1), 184-195.

Cell Signaling & Oncology PI3K PI3K-Akt-mTOR EC 2.7.1.153

Class I PI3K inhibitor

Chemical name

5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine

Parent CAS No.

[944396-07-0]

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Size	Unit Price	Stock
5 mg	$99.00	In Stock
25 mg	$297.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	$154.00	In Stock
2 x 25 mg	$462.00	In Stock

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NVP-BKM120 - BKM 120 | Buparlisib

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