98% purity available from supplier Axon Medchem, prime source of life science reagents for your research" />

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PF 03814735

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2023

CAS [942487-16-3]

MF C23H25F3N6O2
MW 474.48

  • Purity: 98%
  • Optical purity: Optically pure
  • Soluble in DMSO

PF 03814735

Description

Potent, orally bioavailable, ATP-competitive and reversible inhibitor of aurora kinase A (IC50: 0.8 nM) and aurora kinase B (IC50: 5 nM) with potential antineoplastic activity; PF 03814735 also inhibits Flt1, FAK and TrkA with IC50 values of 10, 22, 30 nM respectively; clinical candidate.

KEYWORDS: PF 03814735 | supplier | Aurora inhibitor | PF03814735 | PF-03814735 | CAS [942487-16-3] | Histone | Survivin | Topo | TPX2 | Aurora kinase | antineoplastic activity | Flt1 | FAK | TrkA | clinical candidate

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Size Unit Price Stock
5 mg $132.00 In Stock
25 mg $528.00 In Stock
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2 x 5 mg $242.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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