MLN4924 - Pevonedistat
Axon 2038
CAS [905579-51-3]
MF C21H25N5O4S
MW 443.52
- Purity: 99%
- Optical purity: Optically pure
- Soluble in DMSO
Description
First-in-class inhibitor of NEDD8 Activating Enzyme (NAE) with potent antitumor activity in animal models; cell permeable; MLN4924 inactivates Cullin-RING E3 ubiquitin Ligases (CRLs) by blocking cullin neddylation
Inhibitor of NEDD8 Activating Enzyme (NAE)
Chemical name
((1S,2S,4R)-4-(4-((S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate
Parent CAS No.
[905579-51-3]
Order
Size | Unit Price | Stock | |
---|---|---|---|
1 mg | $66.00 | In Stock | |
5 mg | $132.00 | In Stock | |
25 mg | $462.00 | In Stock |
Special Offers
Size | Unit Price | Stock | |
---|---|---|---|
2 x 5 mg | $198.00 | In Stock |
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