AZD8330

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1999

CAS [869357-68-6]

MF C16H17FIN3O4
MW 461.23

Purity: 98%
Soluble in DMSO

AZD8330

Description

Potent, highly specific non-ATP-competitive MEK inhibitor; AZD8330 specifically inhibits mitogen-activated protein kinase kinase 1 (MEK or MAP/ERK kinase1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation

JI Trujillo. MEK inhibitors: a patent review 2008-2010. Exp. Opin. Ther. Patents. 2011, 21(7), 1045-1069.

MS Chapman & JN Miner. Novel mitogen-activated protein kinase kinase inhibitors. Exp. Opin. Invest. Drugs. 2011, 20(2), 209-220.

C Frémin and S Meloche. From basic research to clinical development of MEK1/2 inhibitors for cancer therapy. J. Hematol. Oncol. 2010, 3, 8.

Cell Signaling & Oncology MAPK EC 2.7.12.2 MEK

MEK 1 inhibitor

Chemical name

2-(2-fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

Parent CAS No.

[869357-68-6]

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Size	Unit Price	Stock
5 mg	$115.50	In Stock
25 mg	$401.50	In Stock

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Size	Unit Price	Stock
2 x 5 mg	$176.00	In Stock
2 x 25 mg	$616.00	In Stock

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Description

Chemical name

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