CNF 2024 - BIIB 021

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1543

CAS [848695-25-0]

MF C14H15ClN6O
MW 318.76

Purity: 99%
Soluble in DMSO

CNF 2024

Description

Oral inhibitor of heat shock protein 90 (Hsp90) under clinical development

B Böll et al. Heat Shock Protein 90 Inhibitor BIIB021 (CNF2024) Depletes NF-κB and Sensitizes Hodgkin's Lymphoma Cells for Natural Killer Cell–Mediated Cytotoxicity. Clin. Cancer Res. 2009, 15(16), 5108–16.

T Taldone et al. Targeting Hsp90: small-molecule inhibitors and their clinical development. Cur. Opin. Pharmacol. 2008, 8(4), 370-374.

Apoptosis Cardiovascular Cell Cycle Regulation Cell Signaling & Oncology Hsp90 EC 3.6

Hsp90 inhibitor

Chemical name

6-Chloro-9-(4-methoxy-3,5-dimethyl-pyridin-2-ylmethyl)-9H-purin-2-ylamine

Parent CAS No.

[848695-25-0]

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Size	Unit Price	Stock
5 mg	$88.00	In Stock
25 mg	$264.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	$132.00	In Stock
2 x 25 mg	$396.00	In Stock

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CNF 2024 - BIIB 021

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CNF 2024 - BIIB 021

Description

Chemical name

Parent CAS No.

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