A 769662

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1466

CAS [844499-71-4]

MF C20H12N2O3S
MW 360.39

Purity: 99%
Soluble in DMSO

A 769662

Description

Potent and selective activator of AMP-activated protein kinase (AMPK) β1 subunit-containing complexes

B Cool et al. Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Metabolism. 2006, 3, 403.

M Sanders et al. Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family. J. Biol. Chem. 2007, 282, 32539.

O Göransson et al. Mechanism of Action of A-769662, a Valuable Tool for Activation of AMP-activated Protein Kinase. J. Biol. Chem. 2007, 282, 32549-32560.

JW Scott et al. Thienopyridone drugs are selective activators of AMP-activated protein kinase β1-containing complexes. Chem. Biol. 2008, 15, 1220.

JT Treebak et al. A-769662 activates AMPK β1-containing complexes but induces glucose uptake through a PI3 kinase-dependent pathway in mouse skeletal muscle. Am. J. Physiol. Cell Physiol. 2009, 297(4), C1041-C1052.

Cell Signaling & Oncology Diabetes & Metabolism Stem Cell AMPK PI3K-Akt-mTOR EC 2.7.11.31

AMPK activator

Chemical name

6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl )-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile

Parent CAS No.

[844499-71-4]

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成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

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A 769662

Description

Chemical name

Parent CAS No.

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