99% purity available from supplier Axon Medchem, prime source of life science reagents for your research" />

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Mocetinostat - MGCD 0103 | MG 0103

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2505

CAS [726169-73-9]

MF C23H20N6O
MW 396.44

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

Mocetinostat

Description

Class I selective HDAC inhibitor (sub-micromolar IC50 values for HDAC1, HDAC2, and HDAC11, ca 2 μM for HDAC3, and >10 μM for HDAC4-8) with broad spectrum antitumor activity in vitro and in vivo. MGCD 0103 induced hyperacetylation of histones, selectively induced apoptosis, caused cell cycle blockade, and exhibited potent and selective antiproliferative activities against a broad spectrum of human cancer cell lines in vitro.

KEYWORDS: Mocetinostat | Supplier | HDAC inhibitor | MGCD 0103 | MG 0103 | MG0103 | MGCD0103 | CAS [726169-73-9] | Histone | HDAC1 | HDAC2 | HDAC3 | HDAC11 | deacetylase | antitumor | hyperacetylation | apoptosis | cell cycle | blockade | isotype-selective

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Size Unit Price Stock
5 mg $88.00 In Stock
25 mg $264.00 In Stock
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Size Unit Price Stock
2 x 5 mg $132.00 In Stock
2 x 25 mg $396.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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