Highly potent, selective and metabolically stable inhibitor of p38 MAPK (p38α cascade IC50: 2.3 nM); an ATP-competitive, readily reversible inhibitor of the α isoform of human p38 MAP kinase, exhibiting a Ki of 5.8 nM; clinical candidate.

*PH 797804 is an (-)-atropisomer, which is 100-fold more potent than its (+)-atropisomer. Be careful that racemate of PH 797804 is wrongly provided by other supplier as drug PH 797804 itself. The less potent (+)-rotating atropisomer is also available (inquire). Be right about your drug.

The racemate, (±)-PH797804 (Axon 2786) is also available.

KEYWORDS: PH 797804 | supplier | p38 MAPK inhibitor | PH797804 | CAS [586379-66-0] | MAPK | MAPK (p38) | Inhibitor | Enzymes